Primary experimental recordPositive observation

PMC9715947::ACT054545

HAZ

Evidence text

Paper-level observation

Section 3.4: HAZ peptide displayed minimal hemolytic toxicity on RBCs even at concentrations higher than therapeutic ones. Hemolytic reaction was only detected at peptide concentrations beyond 20 µM, and a hemolysis percentage around 20 % and beyond was detected at concentrations higher than 120 µM.

textConfidence: medium

Assay observation

Activity

Toxicity

Subtype

Hemolytic

Measure

hemolysis

Comparator

Raw observation

minimal hemolytic toxicity ... Hemolytic reaction was only detected at peptide concentrations beyond 20 µM, and a hemolysis percentage around 20 % and beyond was detected at concentrations higher than 120 µM

Normalized measurement

=20%

Value minimum

Not reported by source

Value maximum

Not reported by source

Target

Homo sapiens

Assay method

Not reported by source

Sequence

GVKFAKRFWRFAKKAFKRFEK

Standardization

ready simple

Source publication

HAZ, a novel peptide with broad-spectrum antibacterial activity

Saudi Pharmaceutical Journal · 2022

DOI 10.1016/j.jsps.2022.09.009 PMC9715947

Parent mention

Related peptide identities

PEPDIA-PLP-001133

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.