PepDiana
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Primary experimental recordPositive observation

PMC9654460::ACT054306

PS14

Evidence text

Paper-level observation

Results of the proteinase inhibition assay showed that PS14, dose-dependently and significantly increased the proteinase inhibition, as: 25.45 ± 1% (5 µM), 39.21 ± 1.5% (10 µM), 49.10 ± 1.89% (15 µM), 69 ± 1.3% (20 µM) and 77 ± 2.8% (25 µM).
textConfidence: medium

Assay observation

Activity
Immunomodulatory
Subtype
Anti-inflammatory
Measure
percent_inhibition
Comparator
=
Raw observation
69 ± 1.3%
Normalized measurement
=69%
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
trypsin
Assay method
Not reported by source
Sequence
PTECQVGTTCKVES
Standardization
ready simple

Source publication

Anti-Cancer and Anti-Inflammatory Activities of a Short Molecule, PS14 Derived from the Virulent Cellulose Binding Domain of Aphanomyces invadans, on Human Laryngeal Epithelial Cells and an In Vivo Zebrafish Embryo Model

Molecules · 2022

DOI 10.3390/molecules27217333 PMC9654460
Parent mention

Related peptide identities

PEPDIA-PLP-002255

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.