PepDiana
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Primary experimental recordPositive observation

PMC13239245::ACT047931

R18D

Evidence text

Paper-level observation

Table 3: R18D 650 nmol/kg Cmax 11,977 ng/mL. Table footnote: Cmax observed 10 min after start of infusion for 650 and 1100 nmol/kg doses.
tableConfidence: medium

Assay observation

Activity
Other
Subtype
Not reported by source
Measure
other
Comparator
=
Raw observation
11,977 ng/mL
Normalized measurement
=11,977 other
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Rattus norvegicus
Assay method
Not reported by source
Sequence
RRRRRRRRRRRRRRRRRR
Standardization
ready simple

Source publication

Pharmacokinetics and Neuroprotective Efficacy of Poly‐Arginine Peptide R18D in Sprague Dawley Rats Subjected to Transient Intraluminal Filament Middle Cerebral Artery Occlusion Stroke

CNS Neuroscience & Therapeutics · 2026

DOI 10.1002/cns.70969 PMC13239245
Parent mention

Related peptide identities

PEPDIA-PLP-002564

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.