PepDiana
Back to Evidence
Primary experimental recordPositive observation

PMC13239245::ACT047928

R18D

Evidence text

Paper-level observation

Table 2: R18D 650 nmol/kg group had 10.62% body weight loss from baseline (Day 0 to Day 1). Vehicle Saline group had 9.35% loss.
tableConfidence: medium

Assay observation

Activity
Toxicity
Subtype
General Toxic
Measure
percent_inhibition
Comparator
=
Raw observation
10.62%
Normalized measurement
=10.62%
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Rattus norvegicus
Assay method
Not reported by source
Sequence
RRRRRRRRRRRRRRRRRR
Standardization
ready simple

Source publication

Pharmacokinetics and Neuroprotective Efficacy of Poly‐Arginine Peptide R18D in Sprague Dawley Rats Subjected to Transient Intraluminal Filament Middle Cerebral Artery Occlusion Stroke

CNS Neuroscience & Therapeutics · 2026

DOI 10.1002/cns.70969 PMC13239245
Parent mention

Related peptide identities

PEPDIA-PLP-002564

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.