PepDiana
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Primary experimental recordPositive observation

PMC13239245::ACT047925

R18D

Evidence text

Paper-level observation

Table 1 and text: R18D 650 nmol/kg reduced hemisphere swelling by 8.3% (p=0.01). Hemisphere swelling 105.26 ± 7.23% vs Vehicle Saline 114.76 ± 7.36%.
tableConfidence: medium

Assay observation

Activity
Metabolic/Cardiovascular
Subtype
Antibacterial
Measure
percent_inhibition
Comparator
=
Raw observation
8.3%
Normalized measurement
=8.3%
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Rattus norvegicus
Assay method
Not reported by source
Sequence
RRRRRRRRRRRRRRRRRR
Standardization
ready simple

Source publication

Pharmacokinetics and Neuroprotective Efficacy of Poly‐Arginine Peptide R18D in Sprague Dawley Rats Subjected to Transient Intraluminal Filament Middle Cerebral Artery Occlusion Stroke

CNS Neuroscience & Therapeutics · 2026

DOI 10.1002/cns.70969 PMC13239245
Parent mention

Related peptide identities

PEPDIA-PLP-002564

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.