Primary experimental recordPositive observation

PMC12936117::ACT037659

M104

Evidence text

Paper-level observation

Following 48 h of incubation with 200 µg/mL peptide M104, the mean cell viability significantly reduced to 90.1% (p-value < 0.05) compared to the untreated control.

textConfidence: medium

Assay observation

Activity

Toxicity

Subtype

Cytotoxic

Measure

cell_viability

Comparator

Raw observation

90.1%

Normalized measurement

=90.1%

Value minimum

Not reported by source

Value maximum

Not reported by source

Target

HDFa

Assay method

MTT assay

Sequence

MEAFIVSAFKHQAEGFKLHYK

Standardization

ready simple

Source publication

Enhanced meropenem activity by a microbiome derived peptide targeting oxacillinase 48 carbapenemase in carbapenem resistant Klebsiella pneumoniae isolates.

Scientific Reports · 2026

DOI 10.1038/s41598-026-37644-2 PMC12936117

Parent mention

Related peptide identities

PEPDIA-PLP-001978

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.