PepDiana
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Primary experimental recordPositive observation

PMC12936117::ACT037598

M104

Evidence text

Paper-level observation

Table 1: Isolate Kp19, MIC of meropenem (µg/mL) in the presence of 15 µg/mL peptide = 4.
tableConfidence: medium

Assay observation

Activity
Antimicrobial
Subtype
Anti-Gram-
Measure
MIC
Comparator
=
Raw observation
4 µg/mL
Normalized measurement
=4 µg/mL
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Klebsiella pneumoniae
Assay method
Broth microdilution (checkerboard assay)
Sequence
MEAFIVSAFKHQAEGFKLHYK
Standardization
ready simple

Source publication

Enhanced meropenem activity by a microbiome derived peptide targeting oxacillinase 48 carbapenemase in carbapenem resistant Klebsiella pneumoniae isolates.

Scientific Reports · 2026

DOI 10.1038/s41598-026-37644-2 PMC12936117
Parent mention

Related peptide identities

PEPDIA-PLP-001978

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.