PepDiana
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Primary experimental recordPositive observation

PMC12444544::ACT025815

PCR12mod6

Evidence text

Paper-level observation

Figure 7A: PCR12mod6 reduced NO production to 69.11% of control at 250 μg/mL in LPS-stimulated RAW 264.7 cells.
figureConfidence: medium

Assay observation

Activity
Immunomodulatory
Subtype
Anti-inflammatory
Measure
percent_inhibition
Comparator
=
Raw observation
69.11% of control
Normalized measurement
=69.11%
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
RAW 264.7
Assay method
Not reported by source
Sequence
PCRKIFCRWKKR
Standardization
ready simple

Source publication

Rational Design of PCR12mod6, a Cathelicidin-HR-Derived Peptide with Enhanced Dual-Action Antimicrobial and Antioxidant Activity

ACS Omega · 2025

DOI 10.1021/acsomega.5c03658 PMC12444544
Parent mention

Related peptide identities

PEPDIA-PLP-002177

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.