PepDiana
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Primary experimental recordPositive observation

PMC12444544::ACT025814

PCR12

Evidence text

Paper-level observation

Figure 7A: PCR12 reduced NO production to 74.25% of control at 500 μg/mL in LPS-stimulated RAW 264.7 cells.
figureConfidence: medium

Assay observation

Activity
Immunomodulatory
Subtype
Anti-inflammatory
Measure
percent_inhibition
Comparator
=
Raw observation
74.25% of control
Normalized measurement
=74.25%
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
RAW 264.7
Assay method
Not reported by source
Sequence
PCRGIFCRTGSR
Standardization
ready simple

Source publication

Rational Design of PCR12mod6, a Cathelicidin-HR-Derived Peptide with Enhanced Dual-Action Antimicrobial and Antioxidant Activity

ACS Omega · 2025

DOI 10.1021/acsomega.5c03658 PMC12444544
Parent mention

Related peptide identities

PEPDIA-PLP-002176

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.