PepDiana
Back to Evidence
Primary experimental recordPositive observation

PMC12429139::ACT025454

L-K5

Evidence text

Paper-level observation

The polarized M2 macrophages treated with 10 ... μM L-K5 reduced MCF-7 cell migration by 80.8% (Section 2.4).
textConfidence: medium

Assay observation

Activity
Anticancer
Subtype
Anti-metastatic
Measure
percent_inhibition
Comparator
=
Raw observation
80.8%
Normalized measurement
=80.8%
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Homo sapiens
Assay method
Not reported by source
Sequence
IKKIVSKIKKLLNH
Standardization
ready simple

Source publication

Lysine-Leucine-Rich Frog Skin Antimicrobial Peptides Inhibit Breast Cancer Metastasis by Reprogramming Tumor-Associated Macrophage Polarization.

International Journal of Molecular Sciences · 2025

DOI 10.3390/ijms26178627 PMC12429139
Parent mention

Related peptide identities

PEPDIA-PLP-001298

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.