PepDiana
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Primary experimental recordPositive observation

PMC12429139::ACT025427

L-K5

Evidence text

Paper-level observation

10 μM ... L-K5 reduced the IL-10 content by 59.6% (Section 2.2).
textConfidence: medium

Assay observation

Activity
Immunomodulatory
Subtype
Anti-inflammatory
Measure
percent_inhibition
Comparator
=
Raw observation
59.6%
Normalized measurement
=59.6%
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Homo sapiens
Assay method
Not reported by source
Sequence
IKKIVSKIKKLLNH
Standardization
ready simple

Source publication

Lysine-Leucine-Rich Frog Skin Antimicrobial Peptides Inhibit Breast Cancer Metastasis by Reprogramming Tumor-Associated Macrophage Polarization.

International Journal of Molecular Sciences · 2025

DOI 10.3390/ijms26178627 PMC12429139
Parent mention

Related peptide identities

PEPDIA-PLP-001298

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.