Primary experimental recordPositive observation

PMC12024264::ACT015981

RV-23

Evidence text

Paper-level observation

According to the best antimicrobial activity evidenced for RV-23, its combination with meropenem provides the best results, with a MIC at ... 6.25 μM (peptide) and 2.5 μg/mL (antibiotic) against E. coli.

textConfidence: medium

Assay observation

Activity

Antimicrobial

Subtype

Antibacterial

Measure

MIC

Comparator

Raw observation

6.25 μM (peptide) and 2.5 μg/mL (antibiotic)

Normalized measurement

=6.25 µM

Value minimum

Not reported by source

Value maximum

Not reported by source

Target

Escherichia coli

Assay method

Not reported by source

Sequence

RIGVLLARLPKLFSLFKLMGKKV

Standardization

ready simple

Source publication

Frog Skin Peptides Hylin-a1, AR-23, and RV-23: Promising Tools Against Carbapenem-Resistant Escherichia coli and Klebsiella pneumoniae Infections

Antibiotics · 2025

DOI 10.3390/antibiotics14040374 PMC12024264

Parent mention Integrated peptide

Related peptide identities

PEPDIA-PLP-003969 PEPDIA-INT-058965

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.