Primary experimental recordPositive observation

PMC11279943::ACT006225

PEP2

Evidence text

Paper-level observation

Section 2.4: 'At P10 and indolicidin AMP concentrations above 0.5× synergistic concentrations, hydrogels completely killed the bacteria' and 'This observed effect at 0.5× MIC is reflective of a concentration of only 1.56 μM and 6.25 μM for indolicidin and P10, respectively.'

textConfidence: medium

Assay observation

Activity

Antimicrobial

Subtype

Anti-Biofilm

Measure

cell_viability

Comparator

unknown

Raw observation

relative to AMP-free control hydrogels; qualitative 'completely killed'; completely killed the bacteria

Normalized measurement

unknown0%

Value minimum

Not reported by source

Value maximum

Not reported by source

Target

Staphylococcus aureus

Assay method

Not reported by source

Sequence

ILPWKWPWWPWRR

Standardization

ready simple

Source publication

Antimicrobial Peptide Screening for Designing Custom Bactericidal Hydrogels.

Pharmaceutics · 2024

DOI 10.3390/pharmaceutics16070860 PMC11279943

Parent mention Integrated peptide

Related peptide identities

PEPDIA-PLP-003672 PEPDIA-INT-078248

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.