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PEPDIA-INT-078248

Gold

Cathelicidin-4, Indolicidin

85

Quality

12

Source DBs

232

Activities

69

Source refs

47

Literature

2

Patents

Integrated record

Sequence and molecular profile

ILPWKWPWWPWRR
Indexed sequence13 aa
1ILPWKWPWWPWRR

Length

13

Molecular weight

1907.31 Da

Formula

C100H131N25O14

Structure type

Linear

Synthesis

Ribosomal

Chirality

Mixed

Family

-

Gene

-

Residue composition

W
5
P
3
R
2
I
1
L
1
K
1

Physicochemical profile

Hydrophobic7

Membrane affinity proxy

Polar0

Solubility proxy

Charged3

Net charge proxy +3

Aromatic5

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

1907.2693 Da

Molecular formula

C100H131N25O14

Theoretical pI

12

Net charge at pH 7

2.7591

GRAVY

-1.0692

Instability index

76.2769

Aromaticity

0.3846

Topological polar surface area

614.92 Ų

cLogP

4.1022

Hydrogen-bond donors

23

Hydrogen-bond acceptors

17

Rotatable bonds

48

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

ILPWKWPWWPWRR

HELM 2.0

validated simple linear

PEPTIDE1{I.L.P.W.K.W.P.W.W.P.W.R.R}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(N)C(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCCN)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N1CCCC1C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N1CCCC1C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)O

Isomeric SMILES

validated

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

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Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-078248,
  title = {Cathelicidin-4, Indolicidin},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-078248},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Cathelicidin-4, Indolicidin. (2026). PepDiana record PEPDIA-INT-078248. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-078248

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (232 records)

Stable recordActivitySubtypeValueTargetAssay methodSource
CTPDB_P078248_ACT_apd_0000AntimicrobialAnti-Gram+Not available in the current structured importUnknownNot reported by sourceAP00150apd / linked
CTPDB_P078248_ACT_apd_0001Antiviral-Not available in the current structured importUnknownNot reported by sourceAP00150apd / linked
CTPDB_P078248_ACT_apd_0002AntimicrobialAntifungalNot available in the current structured importUnknownNot reported by sourceAP00150apd / linked
CTPDB_P078248_ACT_apd_0003AntiviralAnti-HIVNot available in the current structured importUnknownNot reported by sourceAP00150apd / linked
CTPDB_P078248_ACT_apd_0005ToxicityHemolyticNot available in the current structured importUnknownNot reported by sourceAP00150apd / linked
CTPDB_P078248_ACT_apd_0006AntimicrobialAnti-BiofilmNot available in the current structured importUnknownNot reported by sourceAP00150apd / linked
CTPDB_P078248_ACT_apd_0007Wound HealingWound HealingNot available in the current structured importUnknownNot reported by sourceAP00150apd / linked
CTPDB_P078248_ACT_apd_0008Anticancer-Not available in the current structured importUnknownNot reported by sourceAP00150apd / linked
CTPDB_P078248_ACT_avpdb_0009AntiviralGeneral Antiviral28.68 EC50 (μM)Herpes simplex virus 1Plaque assayAVPdb_AVP0426avpdb / unavailable
CTPDB_P078248_ACT_avpdb_0010AntiviralGeneral AntiviralHighHerpes simplex virus 1Viral titerAVPdb_AVP1247avpdb / unavailable
CTPDB_P078248_ACT_baamps_0012AntimicrobialAnti-BiofilmNot available in the current structured importUnknownNot reported by sourceEXP00114baamps / linked
CTPDB_P078248_ACT_baamps_0013AntimicrobialAnti-BiofilmNot available in the current structured importUnknownNot reported by sourceEXP00115baamps / linked
CTPDB_P078248_ACT_baamps_0014AntimicrobialAnti-BiofilmNot available in the current structured importUnknownNot reported by sourceEXP00116baamps / linked
CTPDB_P078248_ACT_camp_0017Antimicrobial-Not available in the current structured importUnknownNot reported by sourceCAMPSQ17120camp / linked
CTPDB_P078248_ACT_camp_0015AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceCAMPSQ254camp / linked
CTPDB_P078248_ACT_camp_0016AntimicrobialAnti-Gram-Not available in the current structured importUnknownNot reported by sourceCAMPSQ254camp / linked
CTPDB_P078248_ACT_cancerppd_0018AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay1812cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0019AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay1827cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0020AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay1964cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0021AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay1979cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0022AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay2116cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0023AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay2131cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0024AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay2268cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0025AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay2283cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0026AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay2420cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0027AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay2435cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0028AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay2563cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0029AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay2578cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0030AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay2706cancerppd / linked
CTPDB_P078248_ACT_cancerppd_0031AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay2721cancerppd / linked
CTPDB_P078248_ACT_dbaasp_0169Antimicrobial-4.2±0.41 µg/mlEscherichia coli ML-35pNot reported by sourceDBAASPS_16253_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0170Antimicrobial-2.2±0.21 µg/mlListeria monocytogenes EGDNot reported by sourceDBAASPS_16253_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0171Antimicrobial-4.7±0.26 µg/mlCandida albicans 820Not reported by sourceDBAASPS_16253_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0143Antimicrobial-1.6 µMMicrococcus luteus ATCC 9341Not reported by sourceDBAASPS_4805_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0144Antimicrobial-1.6 µMMicrococcus luteus ATCC 9341Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0145Antimicrobial-32 µg/mlBotrytis cinereaNot reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0146Antimicrobial-32 µg/mlAlternaria alternataNot reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0147Antimicrobial-8 µg/mlFusarium solaniNot reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0148Antimicrobial-64 µg/mlCladosporium herbarumNot reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0149Antimicrobial-<1 µg/mlClavibacter michiganensis subsp. michiganensis DSM 46294Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0150Antimicrobial->64 µg/mlPectobacterium carotovorum subsp. carotovorum DSM 30168Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0151Antimicrobial-2 µg/mlXanthomonas vesicatoria DSM 50861Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0152Antimicrobial->64 µg/mlPseudomonas syringae pv. tomato DC3000Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0153Antimicrobial->64 µg/mlPseudomonas syringae pv. syringae DSM 10604Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0154Antimicrobial->64 µg/mlPseudomonas corrugata DSM 7228Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0155Antimicrobial-10 µg/mlStaphylococcus aureus ATCC 6538Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0156Antimicrobial->200 µg/mlPseudomonas aeruginosa ATCC 9027Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0157Antimicrobial->200 µg/mlSaccharomyces cerevisiaeNot reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0158Antimicrobial-12 µg/mlHuman breast adenocarcinoma MCF-7Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0159Antimicrobial-30 µg/mlHuman colon adenocarcinoma SW480Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0160Antimicrobial-180 µg/mlHuman melanoma BMKCNot reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0161Antimicrobial-64 µg/mlHuman lung carcinoma H1299Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0162Antimicrobial-20 µg/mlHuman cervical carcinoma HeLa S3Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0163Antimicrobial-31 µg/mlHuman prostate adenocarcinoma PC-3Not reported by sourceDBAASPS_4806_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0164Antimicrobial-0.4 µMMicrococcus luteus ATCC 9341Not reported by sourceDBAASPS_4841_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0165Antimicrobial->64 µg/mlPseudomonas aeruginosa PAO1Not reported by sourceDBAASPS_4841_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0166Antimicrobial-16 µg/mlAcinetobacter baumannii ATCC 19606Not reported by sourceDBAASPS_4841_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0167Antimicrobial-16 µg/mlEscherichia coli W3110Not reported by sourceDBAASPS_4841_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0168Antimicrobial-32 µg/mlKlebsiella pneumoniae NCTC 418Not reported by sourceDBAASPS_4841_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0032Antimicrobial-8 µg/mlStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0033Antimicrobial-8 µg/mlStaphylococcus aureus SAP 0017Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0034Antimicrobial-2 µg/mlStaphylococcus haemolyticusNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0035Antimicrobial-4 µg/mlStaphylococcus epidermidisNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0036Antimicrobial->64 µg/mlEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0037Antimicrobial-4 µg/mlListeria monocytogenes NCTC 7973Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0038Antimicrobial-4 µg/mlStreptococcus pyogenes ATCC 19615Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0039Antimicrobial-0.5 µg/mlCorynebacterium xerosisNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0040Antimicrobial-1.8 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0041Antimicrobial-2.4 µMPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0042Antimicrobial-3.6 µMCryptococcus neoformans ATCC 66031Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0043Antimicrobial-20 µg/mlEscherichia coli KCTC 1682Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0044Antimicrobial-40 µg/mlPseudomonas aeruginosa KCTC 1637Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0045Antimicrobial-20 µg/mlSalmonella typhimurium KCTC 1926Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0046Antimicrobial-10 µg/mlBacillus subtilis KCTC 3068Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0047Antimicrobial-20 µg/mlStaphylococcus epidermidis KCTC 1917Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0048Antimicrobial-10 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0049Antimicrobial-1 µMStaphylococcus aureus ATCC 29213Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0050Antimicrobial-16 µg/mlStaphylococcus aureus CCARM 3696Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0051Antimicrobial-2 µg/mlBacillus subtilis KCTC 2213Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0052Antimicrobial-4 µg/mlMicrococcus luteus KCTC 9341Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0053Antimicrobial-8 µg/mlEnterococcus faecium CCARM 5028Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0054Antimicrobial-64 µg/mlListeria monocytogenes KCTC 19111Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0055Antimicrobial-64 µg/mlPseudomonas aeruginosa CCARM 2161Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0056Antimicrobial-8 µg/mlEscherichia coli KCTC 1039Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0057Antimicrobial-16 µg/mlKlebsiella oxytoca KCTC 1686Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0058Antimicrobial-8 µg/mlCitrobacter freundii KCTC 2359Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0059Antimicrobial-8 µg/mlSalmonella enterica subsp. enterica KCTC 2930Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0060Antimicrobial-38 µg/mlPseudomonas aeruginosa H1001Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0061Antimicrobial-0.000035 µMLeishmania donovaniNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0062Antimicrobial-8 µMStaphylococcus aureus CCARM 3001Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0063Antimicrobial-8 µMStaphylococcus aureus CCARM 3543Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0064Antimicrobial-32 µMPseudomonas aeruginosa CCARM 2095Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0065Antimicrobial-32 µMPseudomonas aeruginosa CCARM 2109Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0066Antimicrobial-8 µg/mlStaphylococcus aureus KCTC 1621Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0067Antimicrobial-16 µg/mlCandida albicans KCTC 7965Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0068Antimicrobial-5 µg/mlEscherichia coli W160-37Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0069Antimicrobial-2-4 µg/mlStaphylococcus aureus ATCC 8530Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0070Antimicrobial-20-25 µg/mlSaccharomyces cerevisiae PEP 4/3Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0071Antimicrobial-20-25 µg/mlCandida utilis CBS4511Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0072Antimicrobial-60 µMHIV-1Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0073Antimicrobial-57 µMHIV-1Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0074Antimicrobial-32 µg/mlEscherichia coli ATCC 11775Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0075Antimicrobial-16 µg/mlPseudomonas aeruginosa ATCC 25668Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0076Antimicrobial-32 µg/mlBacillus subtilis ATCC 6633Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0077Antimicrobial-16 µg/mlStaphylococcus aureus ATCC 9144Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0078Antimicrobial-64 µg/mlAcinetobacter sp.Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0079Antimicrobial-8 µg/mlEscherichia coliNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0080Antimicrobial->128 µg/mlAcinetobacter baumannii Ab5753Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0081Antimicrobial->128 µg/mlAcinetobacter baumannii Ab5755Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0082Antimicrobial->128 µg/mlAcinetobacter baumannii Ab1408Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0083Antimicrobial->128 µg/mlEscherichia coli Ec513Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0084Antimicrobial->128 µg/mlPseudomonas aeruginosa Pa1409Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0085Antimicrobial->128 µg/mlPseudomonas aeruginosa Pa4216Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0086Antimicrobial->128 µg/mlStaphylococcus aureus Sa1390Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0087Antimicrobial-3.6 µMStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0088Antimicrobial-4 µMEscherichia coli DH5alphaNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0089Antimicrobial-8 µMSalmonella typhimuriumNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0090Antimicrobial-10 µMKlebsiella pneumoniaeNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0091Antimicrobial-10 µMPseudomonas aeruginosaNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0092Antimicrobial-15.62-31.25 µg/mlStreptococcus pneumoniaeNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0093Antimicrobial-31.25 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0094Antimicrobial-31.25 µg/mlStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0095Antimicrobial-31.25 µg/mlStaphylococcus aureusNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0096Antimicrobial-31.25 µg/mlPseudomonas aeruginosa ATCC 15442Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0097Antimicrobial->250 µg/mlAcinetobacter baumannii ATCC 15308Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0098Antimicrobial->250 µg/mlEnterobacter cloacaeNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0099Antimicrobial->250 µg/mlCitrobacter sp.Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0100Antimicrobial->250 µg/mlKlebsiella pneumoniaeNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0101Antimicrobial->128 µg/mlMycobacterium tuberculosisNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0102Antimicrobial-32-64 µg/mlMycobacterium tuberculosisNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0103Antimicrobial-128 µg/mlMycobacterium aviumNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0104Antimicrobial-16 µg/mlStaphylococcus aureus ATCC 29213Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0105Antimicrobial-32 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0106Antimicrobial-32 µg/mlPseudomonas aeruginosa PAO1 H103Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0107Antimicrobial-2.5 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0108Antimicrobial-7 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0109Antimicrobial-3-4 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0110Antimicrobial-30 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0111Antimicrobial-6 µMEscherichia coli ATCC 11775Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0112Antimicrobial-10 µMEscherichia coli ATCC 35218Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0113Antimicrobial-4 µMEscherichia coli ML-35pNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0114Antimicrobial-8 µMSalmonella enterica subsp. enterica serovar Typhimurium ATCC 14028Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0115Antimicrobial-3 µMSalmonella enterica subsp. enterica serovar Typhi Vi+Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0116Antimicrobial-4 µMSalmonella enterica subsp. enterica serovar Abony NCTC 6017Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0117Antimicrobial-2 µMKlebsiella pneumoniae ATCC 13883Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0118Antimicrobial-8 µMKlebsiella pneumoniae ATCC 700603Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0119Antimicrobial-5 µMPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0120Antimicrobial-4 µMStaphylococcus aureus ATCC 33592Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0121Antimicrobial-3 µMStaphylococcus epidermidis MTCC 435Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0122Antimicrobial-4 µMStaphylococcus saprophyticus MTCC 6155Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0123Antimicrobial-3 µMBacillus subtilis MTCC 121Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0124Antimicrobial-2.5 µMMicrococcus luteus MTCC 166Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0125Antimicrobial-5 µMMycobacterium smegmatis mc2-155Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0126Antimicrobial-35 µMMurine macrophage cells RAW 264.7Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0127Antimicrobial-16 µg/mlEscherichia coli HB101Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0128Antimicrobial-64 µg/mlHuman breast adenocarcinoma MCF-7Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0129Antimicrobial-345 µg/mlHuman colon adenocarcinoma SW480Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0130Antimicrobial-200 µg/mlHuman melanoma BMKCNot reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0131Antimicrobial-270 µg/mlHuman lung carcinoma H1299Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0132Antimicrobial-345 µg/mlHuman cervical carcinoma HeLa S3Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0133Antimicrobial-290 µg/mlHuman prostate adenocarcinoma PC-3Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0134Antimicrobial-8 µMPseudomonas aeruginosa PAO1Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0135Antimicrobial-32 µMPseudomonas aeruginosa 910Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0136Antimicrobial-32 µMPseudomonas aeruginosa 919Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0137Antimicrobial-64-128 µMPseudomonas aeruginosa 253Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0138Antimicrobial-0.98 µg/mlTransmissible gastroenteritis coronavirus (TGEV/PCoV)Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0139Antimicrobial-3.91 µg/mlTransmissible gastroenteritis coronavirus (TGEV/PCoV)Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0140Antimicrobial-15.63 µg/mlTransmissible gastroenteritis coronavirus (TGEV/PCoV)Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0141Antimicrobial-62.5 µg/mlTransmissible gastroenteritis coronavirus (TGEV/PCoV)Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dbaasp_0142Antimicrobial->62.5 µg/mlTransmissible gastroenteritis coronavirus (TGEV/PCoV)Not reported by sourceDBAASPS_491_chain0dbaasp / linked
CTPDB_P078248_ACT_dramp_0172Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP02857dramp / linked
CTPDB_P078248_ACT_dramp_0173AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceDRAMP02857dramp / linked
CTPDB_P078248_ACT_dramp_0174AntimicrobialAnti-Gram+Not available in the current structured importUnknownNot reported by sourceDRAMP02857dramp / linked
CTPDB_P078248_ACT_dramp_0175AntimicrobialAnti-Gram-Not available in the current structured importUnknownNot reported by sourceDRAMP02857dramp / linked
CTPDB_P078248_ACT_dramp_0176Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP05078dramp / linked
CTPDB_P078248_ACT_dramp_0177Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP20465dramp / linked
CTPDB_P078248_ACT_dramp_0178Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP37294dramp / linked
CTPDB_P078248_ACT_dramp_0179AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceDRAMP37294dramp / linked
CTPDB_P078248_ACT_dramp_0180UnknownAntivirialNot available in the current structured importUnknownNot reported by sourceDRAMP37294dramp / linked
CTPDB_P078248_ACT_hemolytik_0203ToxicityHemolytic100.0 µg/mlErythrocytesNot reported by source1038hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0204ToxicityHemolytic64.0 µMErythrocytesNot reported by source1450hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0205ToxicityHemolytic50.0 µMErythrocytesNot reported by source1470hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0206ToxicityHemolyticNot available in the current structured importErythrocytesNot reported by source1495hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0207ToxicityHemolytic310.0 µg/mlErythrocytesNot reported by source1719hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0181ToxicityHemolytic200.0 µg/mlErythrocytesNot reported by source2212hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0182ToxicityHemolytic80.0 µg/mlErythrocytesNot reported by source2449hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0183ToxicityHemolytic25.0 µg/mLErythrocytesNot reported by source3026hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0184ToxicityHemolytic25.0 µg/mLErythrocytesNot reported by source3027hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0185ToxicityHemolytic25.0 µg/mLErythrocytesNot reported by source3028hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0186ToxicityHemolytic25.0 µg/mLErythrocytesNot reported by source3029hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0187ToxicityHemolytic50.0 µg/mLErythrocytesNot reported by source3030hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0188ToxicityHemolytic50.0 µg/mLErythrocytesNot reported by source3031hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0189ToxicityHemolytic50.0 µg/mLErythrocytesNot reported by source3032hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0190ToxicityHemolytic50.0 µg/mLErythrocytesNot reported by source3033hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0191ToxicityHemolytic100.0 µg/mLErythrocytesNot reported by source3034hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0192ToxicityHemolytic100.0 µg/mLErythrocytesNot reported by source3035hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0193ToxicityHemolytic100.0 µg/mLErythrocytesNot reported by source3036hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0194ToxicityHemolytic100.0 µg/mLErythrocytesNot reported by source3037hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0195ToxicityHemolytic200.0 µg/mLErythrocytesNot reported by source3038hemolytik / linked
CTPDB_P078248_ACT_hemolytik_0196ToxicityHemolytic200.0 µg/mLErythrocytesNot reported by source3039hemolytik / linked

Showing the first 200 normalized records. Use the stable activity API to inspect the complete set.

Sequence-linked cross-layer evidence

Linked primary-literature evidence

9

Records

2

Papers

9

Positive

0

Negative

1

Primary identities

These observations were collected directly from primary literature and linked by identical normalized sequence. They remain a separate evidence layer and do not overwrite Integrated source-database annotations.

View PEPDIA-PLP-003672View all experimental records

Provenance

Source database records (69)

Source-specific sequence or modification context. One or more source records use a sequence notation that differs from the canonical backbone. Open each raw sequence before interpreting stereochemistry, terminal groups, or non-standard residues.

apd

AP00150

Raw sequence

ILPWKWPWWPWRR

avpdb

AVPdb_AVP0426

Raw sequence

ILPWKWPWWPWRR

avpdb

AVPdb_AVP1247

Raw sequence

ILPWKWPWWPWRR

hipdb

HIPdb_HIP1059

Raw sequence

ILPWKWPWWPWRR

baamps

EXP00114

Raw sequence

ILPWKWPWWPWRR

baamps

EXP00115

Raw sequence

ILPWKWPWWPWRR

baamps

EXP00116

Raw sequence

ILPWKWPWWPWRR

camp

CAMPSQ254

Raw sequence

ILPWKWPWWPWRR

camp

CAMPSQ17120

Raw sequence

ILPWKWPWWPWRR

cancerppd

1812

Raw sequence

ILPWKWPWWPWRR

cancerppd

1827

Raw sequence

ILPWKWPWWPWRR

cancerppd

1964

Raw sequence

ILPWKWPWWPWRR

cancerppd

1979

Raw sequence

ILPWKWPWWPWRR

cancerppd

2116

Raw sequence

ILPWKWPWWPWRR

cancerppd

2131

Raw sequence

ILPWKWPWWPWRR

cancerppd

2268

Raw sequence

ILPWKWPWWPWRR

cancerppd

2283

Raw sequence

ILPWKWPWWPWRR

cancerppd

2420

Raw sequence

ILPWKWPWWPWRR

cancerppd

2435

Raw sequence

ILPWKWPWWPWRR

cancerppd

2563

Raw sequence

ILPWKWPWWPWRR

cancerppd

2578

Raw sequence

ILPWKWPWWPWRR

cancerppd

2706

Raw sequence

ILPWKWPWWPWRR

cancerppd

2721

Raw sequence

ILPWKWPWWPWRR

dbaasp

DBAASPS_491_chain0

Raw sequence

ILPWKWPWWPWRR

dbaasp

DBAASPS_4805_chain0

Raw sequence

ILPWKWPWWPWRR

dbaasp

DBAASPS_4806_chain0

Raw sequence

ILPWKWPWWPWRR

dbaasp

DBAASPS_4841_chain0

Raw sequence

ilpwkwpwwpwrr

dbaasp

DBAASPS_16253_chain0

Raw sequence

ILPWKWPWWPWRR

dramp

DRAMP02857

Raw sequence

ILPWKWPWWPWRR

dramp

DRAMP05078

Raw sequence

ILPWKWPWWPWRR

dramp

DRAMP20465

Raw sequence

ILPWKWPWWPWRR

dramp

DRAMP37294

Raw sequence

ILPWKWPWWPWRR

hemolytik

2212

Raw sequence

ILPWKWPWWPWRR

hemolytik

2449

Raw sequence

ILPWKWPWWPWRR

hemolytik

3026

Raw sequence

ILPWKWPWWPWRR

hemolytik

3027

Raw sequence

I*LPWKWPWWPWRR

hemolytik

3028

Raw sequence

ILPWKWPW*WPWRR

hemolytik

3029

Raw sequence

I*LPWKWPW*WPWRR

hemolytik

3030

Raw sequence

ILPWKWPWWPWRR

hemolytik

3031

Raw sequence

I*LPWKWPWWPWRR

hemolytik

3032

Raw sequence

ILPWKWPW*WPWRR

hemolytik

3033

Raw sequence

I*LPWKWPW*WPWRR

hemolytik

3034

Raw sequence

ILPWKWPWWPWRR

hemolytik

3035

Raw sequence

I*LPWKWPWWPWRR

hemolytik

3036

Raw sequence

ILPWKWPW*WPWRR

hemolytik

3037

Raw sequence

I*LPWKWPW*WPWRR

hemolytik

3038

Raw sequence

ILPWKWPWWPWRR

hemolytik

3039

Raw sequence

I*LPWKWPWWPWRR

hemolytik

3040

Raw sequence

ILPWKWPW*WPWRR

hemolytik

3041

Raw sequence

I*LPWKWPW*WPWRR

hemolytik

3655

Raw sequence

ILPWKWPWWPWRR

hemolytik

3656

Raw sequence

ILPWKWPWWPWRR

hemolytik

3657

Raw sequence

ILPWKWPWWPWRR

hemolytik

3947

Raw sequence

ILPWKWPWWPWRR

hemolytik

1038

Raw sequence

ILPWKWPWWPWRR

hemolytik

1450

Raw sequence

ILPWKWPWWPWRR

hemolytik

1470

Raw sequence

ILPWKWPWWPWRR

hemolytik

1495

Raw sequence

ILPWKWPWWPWRR

hemolytik

1719

Raw sequence

ILPWKWPWWPWRR

parapep

1301

Raw sequence

ILPWKWPWWPWRR

parapep

1302

Raw sequence

ILPWKWPWWPWRR

parapep

1361

Raw sequence

ILPWKWPWWPWRR

plantpepdb

PPepDB_3324

Raw sequence

ILPWKWPWWPWRR

satpdb

satpdb10356

Raw sequence

ILPWKWPWWPWRR

satpdb

satpdb10628

Raw sequence

ILPWKWPWWPWRR

satpdb

satpdb17052

Raw sequence

ILPWKWPW*WPWRR

satpdb

satpdb18060

Raw sequence

I*LPWKWPW*WPWRR

satpdb

satpdb20242

Raw sequence

I*LPWKWPWWPWRR

satpdb

satpdb22480

Raw sequence

ILPWKWPWWPWRR

Citation trail

Literature (47 records)

Indolicidin, a novel bactericidal tridecapeptide amide from neutraphils

Selsted ME, Novotny MJ, Morris WL, Tang YQ, Smith W, Cullor JS.1992

J Biol Chem1992PMID 1537821

Antiviral activity of antimicrobial cationic peptides against Junin virus and herpes simplex virus.

Albiol Matanic VC, Castilla V.

Int J Antimicrob Agents2004PMID 15081088

Peptide inhibitors against herpes simplex virus infections.

Galdiero S, Falanga A, Tarallo R, Russo L, Galdiero E, Cantisani M, Morelli G, Galdiero M.

J Pept Sci2013PMID 23389903

{"pubmed_id": "16998183.0", "paper": "Covalent binding of the natural antimicrobial peptide indolicidin to DNA abasic sites.", "authors": "Marchand C, Krajewski K, Lee HF, Antony S, Johnson AA, Amin R, Roller P, Kvaratskhelia M, Pommier Y.", "reference": "Nucleic Acids Res. 2006;34(18):5157-65. Epub 2006 Sep 22."}

{"pubmed_id": "16998183.0", "paper": "Covalent binding of the natural antimicrobial peptide indolicidin to DNA abasic sites.", "authors": "Marchand C, Krajewski K, Lee HF, Antony S, Johnson AA, Amin R, Roller P, Kvaratskhelia M, Pommier Y.", "reference": "Nucleic Acids Res. 2006;34(18):5157-65. Epub 2006 Sep 22."}

--

[{"title": "[In Vitro Activities of Antibiotics and Antimicrobial Cationic Peptides Alone and in Combination against Methicillin-Resistant Staphylococcus aureus Biofilms](https://www.doi.org/10.1128/AAC.01180-12)", "authors": "E. Mataraci, S. Dosler", "publication": "2012.Antimicrobial Agents and Chemotherapy 12:6366-6371"}]

[{"title": "[In Vitro Activities of Antibiotics and Antimicrobial Cationic Peptides Alone and in Combination against Methicillin-Resistant Staphylococcus aureus Biofilms](https://www.doi.org/10.1128/AAC.01180-12)", "authors": "E. Mataraci, S. Dosler", "publication": "2012.Antimicrobial Agents and Chemotherapy 12:6366-6371"}]

--

{"pubmed_id": "[None](http://www.ncbi.nlm.nih.gov/pubmed/None)", "year": "2005"}

-

--

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 10898680

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 19445503

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 16352849

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 20385874

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 19171306

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 12615333

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 19285481

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 19428758

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 12207877

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 10924341

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 8849687

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 15482931

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 20599694

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 25730460

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 25935286

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 26046345

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 30570475

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 25941221

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 31485742

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 11302828

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 31849888

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

Friedrich CL, Moyles D, Beveridge TJ, Hancock RE

Antimicrob Agents Chemother2000PMID 33016025

Structure-function relationships in the tryptophan-rich, antimicrobial peptide indolicidin.

Staubitz P, Peschel A, Nieuwenhuizen WF, Otto M, Götz F, Jung G, Jack RW

J Pept Sci2001PMID 11695650

Structure-function relationships in the tryptophan-rich, antimicrobial peptide indolicidin.

Staubitz P, Peschel A, Nieuwenhuizen WF, Otto M, Götz F, Jung G, Jack RW

J Pept Sci2001PMID 10795591

Structure-function relationships in the tryptophan-rich, antimicrobial peptide indolicidin.

Staubitz P, Peschel A, Nieuwenhuizen WF, Otto M, Götz F, Jung G, Jack RW

J Pept Sci2001PMID 23951222

Structure-function relationships in the tryptophan-rich, antimicrobial peptide indolicidin.

Staubitz P, Peschel A, Nieuwenhuizen WF, Otto M, Götz F, Jung G, Jack RW

J Pept Sci2001PMID 33532575

Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity

Smirnova MP, Kolodkin NI, Kolobov AA, Afonin VG, Afonina IV, Stefanenko LI, Shpen VM, Shamova OV

Peptides2020PMID 32593681

Indolicidin, a novel bactericidal tridecapeptide amide from neutrophils.##Structure of the bovine antimicrobial peptide indolicidin bound to dodecylphosphocholine and sodium dodecyl sulfate micelles.##Direct antimicrobial properties of substance P.

Selsted ME, Novotny MJ, Morris WL, Tang YQ, Smith W, Cullor JS.##Rozek A, Friedrich CL, Hancock RE.##Kowalska K, Carr DB, Lipkowski AW.

J Biol Chem1992PMID 11123901

Indolicidin, a novel bactericidal tridecapeptide amide from neutrophils.##Structure of the bovine antimicrobial peptide indolicidin bound to dodecylphosphocholine and sodium dodecyl sulfate micelles.##Direct antimicrobial properties of substance P.

Selsted ME, Novotny MJ, Morris WL, Tang YQ, Smith W, Cullor JS.##Rozek A, Friedrich CL, Hancock RE.##Kowalska K, Carr DB, Lipkowski AW.

J Biol Chem1992PMID 12074933

{"doi": "10.15889/j.issn.1002-1302.2017.07.010.", "reference": "[J].江苏农业科学,2017,45(07):44-46.DOI:10.15889/j.issn.1002-1302.2017.07.010.", "author": "武慧,宋明霞,宁思淇", "title": "紫花苜蓿的抗菌肽基因Rev4遗传转化"}

{"doi": "10.15889/j.issn.1002-1302.2017.07.010.", "reference": "[J].江苏农业科学,2017,45(07):44-46.DOI:10.15889/j.issn.1002-1302.2017.07.010.", "author": "武慧,宋明霞,宁思淇", "title": "紫花苜蓿的抗菌肽基因Rev4遗传转化"}

--

IP evidence

Patents (2)

US 20040019181

dramp

US 9017656

dramp

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:11.941613+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET
{
  "toxicity": [
    {
      "unit": "µg/ml",
      "value": "50",
      "source_db": "dbaasp",
      "assay_method": "5% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "254",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "100",
      "source_db": "dbaasp",
      "assay_method": "35% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "100",
      "source_db": "dbaasp",
      "assay_method": "100% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Rat erythrocytes"
    },
    {
      "unit": "µM",
      "value": "15",
      "source_db": "dbaasp",
      "assay_method": "23% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "15",
      "source_db": "dbaasp",
      "assay_method": "4% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Sheep erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "250",
      "source_db": "dbaasp",
      "assay_method": "56.98% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "source_db": "dbaasp",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human lung normal epithelial cells NL20"
    },
    {
      "unit": "µg/ml",
      "value": "64",
      "source_db": "dbaasp",
      "assay_method": "10% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "25",
      "source_db": "dbaasp",
      "assay_method": "5% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Rat erythrocytes"
    },
    {
      "unit": "µM",
      "value": "11",
      "source_db": "dbaasp",
      "assay_method": "LD50",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Murine macrophage cells J774A.1"
    },
    {
      "unit": "µg/ml",
      "value": "603",
      "source_db": "dbaasp",
      "assay_method": "50% Cytotoxicity",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Swine testis cells ST"
    },
    {
      "unit": "µM",
      "value": "15.6",
      "source_db": "dbaasp",
      "assay_method": "100% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "15.6",
      "source_db": "dbaasp",
      "assay_method": "100% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "80",
      "source_db": "dbaasp",
      "assay_method": "38% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "40",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "9",
      "source_db": "dbaasp",
      "assay_method": "LD50",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human fibroblasts WI-38"
    },
    {
      "unit": "µg/ml",
      "value": "125",
      "source_db": "dbaasp",
      "assay_method": "<5% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "166.7±25.82",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    }
  ]
}
Source metadata
[
  {
    "source_db": "apd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "avpdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "hipdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "baamps",
    "organism_name": "Unknown"
  },
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "cancerppd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "hemolytik",
    "organism_name": "Unknown"
  },
  {
    "source_db": "parapep",
    "organism_name": "Unknown"
  },
  {
    "source_db": "plantpepdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]
Structure metadata
{
  "pdb_id": [
    "1G8C, 1G89 resolved by NMR.",
    "Not found"
  ],
  "source_db": "dramp"
}