PepDiana
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Primary experimental recordPositive observation

PMC10126514::ACT000310

P9

Evidence text

Paper-level observation

Figure 4: compared with the Aβ positive control group, the fluorescence intensity of P9 and P12 polypeptides has increased, but the difference is not statistically significant (p > 0.05), indicating that P9 and P12 have no inhibitory effect on Aβ aggregation.
textConfidence: medium

Assay observation

Activity
Other
Subtype
Anti-Aggregation
Measure
percent_inhibition
Comparator
>
Raw observation
fluorescence intensity increased, no inhibitory effect (p>0.05)
Normalized measurement
>0.05
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Aβ1-42
Assay method
Not reported by source
Sequence
YVRHHHYVRHHH
Standardization
ready simple

Source publication

The interaction of peptide inhibitors and Aβ protein: Binding mode analysis, inhibition of the formation of Aβ aggregates, and then exert neuroprotective effects.

Frontiers in Aging Neuroscience · 2023

DOI 10.3389/fnagi.2023.1139418 PMC10126514
Parent mention

Related peptide identities

PEPDIA-PLP-003360

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.