AntimicrobialAnti-Gram-Positive observation
Record detail Table 4: Temporin-SHa MIC on A. baumannii (DSM 30007) = 6.25 µM.
- Measure
- MIC
- Value
- 6.25 µM
- Target
- Acinetobacter baumannii
- Assay
- Not reported by source
Source publication
Design, Synthesis and Characterization of [G10a]-Temporin SHa Dendrimers as Dual Inhibitors of Cancer and Pathogenic Microbes
Biomolecules · 2022
- Sequence status
- reported
- Standardization
- Sequence ready
- Source location
- unknown
- Activity records
- 19
Sequence evidence
Reported molecular identity
FLSGIVGMLGKLF
FLSGIVGMLGKLF
Resolved peptide links
Experimental observations
Records linked to this mention
AntimicrobialAnti-Gram-Positive observation
Record detail Table 4: Temporin-SHa MIC on E. cloacae (DSM 30054) = 50 µM.
- Measure
- MIC
- Value
- 50 µM
- Target
- Enterobacter cloacae
- Assay
- Not reported by source
AntimicrobialAnti-Gram-Positive observation
Record detail Table 4: Temporin-SHa MIC on E. coli (ATCC 8739) = 50 µM.
- Measure
- MIC
- Value
- 50 µM
- Target
- Escherichia coli
- Assay
- Not reported by source
AntimicrobialAnti-Gram-Positive observation
Record detail Table 4: Temporin-SHa MIC on P. aeruginosa (ATCC 9027) = 50 µM.
- Measure
- MIC
- Value
- 50 µM
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAnti-Gram-Positive observation
Record detail Table 4: Temporin-SHa MIC on H. pylori (ATCC 43504) = 3.12 µM.
- Measure
- MIC
- Value
- 3.12 µM
- Target
- Helicobacter pylori
- Assay
- Not reported by source
AntimicrobialAnti-Gram-Positive observation
Record detail Table 4: Temporin-SHa MIC on K. pneumoniae (DSM 26371) = 50 µM.
- Measure
- MIC
- Value
- 50 µM
- Target
- Klebsiella pneumoniae
- Assay
- Not reported by source
AntimicrobialAnti-Gram+Positive observation
Record detail Table 4: Temporin-SHa MIC on B. subtilis (ATCC 6633) = 1.56 µM.
- Measure
- MIC
- Value
- 1.56 µM
- Target
- Bacillus subtilis
- Assay
- Not reported by source
AntimicrobialAnti-Gram+Positive observation
Record detail Table 4: Temporin-SHa MIC on E. faecalis (DSM 2570) = 12.5 µM.
- Measure
- MIC
- Value
- 12.5 µM
- Target
- Enterococcus faecalis
- Assay
- Not reported by source
AntimicrobialAnti-Gram+Positive observation
Record detail Table 4: Temporin-SHa MIC on E. faecium (DSM 20477) = 6.25 µM.
- Measure
- MIC
- Value
- 6.25 µM
- Target
- Enterococcus faecium
- Assay
- Not reported by source
AntimicrobialAnti-Gram+Positive observation
Record detail Table 4: Temporin-SHa MIC on S. aureus (ATCC 6538) = 3.12 µM.
- Measure
- MIC
- Value
- 3.12 µM
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
AnticancerCytotoxicPositive observation
Record detail Table 5: SHa IC50 on MCF-7 = 20.36 ± 5.64 µM.
- Measure
- other
- Value
- 20.36 µM
- Target
- MCF-7
- Assay
- Not reported by source
AnticancerCytotoxicNegative / threshold
Record detail Table 5: SHa IC50 on HepG2 >100 µM.
- Measure
- other
- Value
- >100 µM
- Target
- HepG2
- Assay
- Not reported by source
AnticancerCytotoxicNegative / threshold
Record detail Table 5: SHa IC50 on A549 >100 µM.
- Measure
- other
- Value
- >100 µM
- Target
- A549
- Assay
- Not reported by source
AnticancerCytotoxicNegative / threshold
Record detail Table 5: SHa IC50 on A2780 >100 µM.
- Measure
- other
- Value
- >100 µM
- Target
- A2780
- Assay
- Not reported by source
AnticancerCytotoxicNegative / threshold
Record detail Table 5: SHa IC50 on MiaPaCa >100 µM.
- Measure
- other
- Value
- >100 µM
- Target
- MiaPaCa
- Assay
- Not reported by source
AnticancerCytotoxicNegative / threshold
Record detail Table 5: SHa IC50 on PC-3 >100 µM.
- Measure
- other
- Value
- >100 µM
- Target
- PC-3
- Assay
- Not reported by source
AnticancerCytotoxicNegative / threshold
Record detail Table 5: SHa IC50 on MNT-1 >100 µM.
- Measure
- other
- Value
- >100 µM
- Target
- MNT-1
- Assay
- Not reported by source
ToxicityCytotoxicNegative / threshold
Record detail Table 5: SHa IC50 on IMR-90 >100 µM.
- Measure
- other
- Value
- >100 µM
- Target
- IMR-90
- Assay
- Not reported by source
ToxicityHemolyticPositive observation
Record detail Section 3.9: Temporin SHa estimated HC50 = 266.20 ± 41.27 µM.
- Measure
- HD50
- Value
- 266.2 µM
- Target
- Homo sapiens
- Assay
- Not reported by source
Local peptide labels such as P1, PEP1, or peptide 1 are grouped only within this paper and are not assumed to represent the same molecule across publications.