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Paper-scoped peptide mentionSequence reported

RKW

PMC12947016::PEP000001

Source publication

Selective Interaction of the Antimicrobial Peptide RKW with Bacterial Lipid Bilayers: A Biophysical Approach.

ACS Omega · 2026

Sequence status
reported
Standardization
Sequence ready
Source location
text
Activity records
3

Sequence evidence

Reported molecular identity

RKWILKWLRTWKK

The antimicrobial peptide RKW (RKWILKWLRTWKK-NH2) was purchased from GenScript Biotech (Leiden, Netherlands) at >95% purity.

Resolved peptide links

Experimental observations

Records linked to this mention

ToxicityGeneral ToxicPositive observation
Record detail

After 48 h of treatment, the peptide's impact on worm survival was evaluated. As shown in Figure 8B,C, RKW did not exhibit any toxicity at the tested concentrations.

Measure
survival_rate
Value
RKW did not exhibit any toxicity at the tested concentrations
Target
Caenorhabditis elegans
Assay
Not reported by source
Source publication
ToxicityGeneral ToxicPositive observation
Record detail

As shown in Figure 9, treatment with peptide at both 10 and 50 μM concentrations did not significantly affect egg-laying (Figure 9A–C) or embryonic survival (Figure 9B,C) compared to controls.

Measure
survival_rate
Value
treatment with peptide at both 10 and 50 μM concentrations did not significantly affect egg-laying or embryonic survival
Target
Caenorhabditis elegans
Assay
Not reported by source
Source publication
ToxicityGeneral ToxicNegative / threshold
Record detail

The results revealed no significant increase in DNA damage-induced apoptosis following peptide exposure (Figure 10).

Measure
other
Value
no significant increase in DNA damage-induced apoptosis
Target
Caenorhabditis elegans
Assay
Not reported by source
Source publication

Local peptide labels such as P1, PEP1, or peptide 1 are grouped only within this paper and are not assumed to represent the same molecule across publications.