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Paper-scoped peptide mentionSequence reported

pep2

PMC12713444::PEP000002

Source publication

Antimicrobial Peptide-Loaded Mesoporous Silica Nanoparticles: A pH-Triggered Controlled Release against Biofilms.

ACS Omega · 2025

Sequence status
reported
Standardization
Sequence ready
Source location
unknown
Activity records
5

Sequence evidence

Reported molecular identity

FIGAIARLLSKIF

FIGAIARLLSKIF

Resolved peptide links

Experimental observations

Records linked to this mention

AntimicrobialAntibacterialPositive observation
Record detail

Results text: 'complete bacterial inhibition was observed at ... 6.25 μg/mL for BmKn2' (free peptide). Figure 3b caption confirms planktonic growth inhibition.

Measure
MIC
Value
6.25 μg/mL
Target
Staphylococcus aureus
Assay
Not reported by source
Source publication
AntimicrobialAntibacterialPositive observation
Record detail

Results text: 'complete bacterial inhibition was observed at ... 6.25 μg/mL for BmKn2' (peptide-loaded MSNs). Figure 3b caption confirms planktonic growth inhibition.

Measure
MIC
Value
6.25 μg/mL
Target
Staphylococcus aureus
Assay
Not reported by source
Source publication
AntimicrobialAnti-BiofilmPositive observation
Record detail

Results text: 'The MBEC for both peptides was determined to be 50 μg/mL, at which no viable colonies were detected after 24 h.' Figure 3d caption confirms biofilm eradication.

Measure
other
Value
50 μg/mL (MBEC)
Target
Staphylococcus aureus
Assay
Not reported by source
Source publication
ToxicityCytotoxicPositive observation
Record detail

Results text: 'BmKn2-MSNs exhibited reduced cytotoxicity compared to the free peptide, particularly at higher concentrations (IC50 = 201 μg/mL).' Figure 5b.

Measure
other
Value
201 μg/mL
Target
MRC-5
Assay
Not reported by source
Source publication
ToxicityCytotoxicPositive observation
Record detail

Results text: 'BmKn2-MSNs exhibited reduced cytotoxicity compared to the free peptide, particularly at higher concentrations.' Figure 5b shows free BmKn2 cytotoxicity curve.

Measure
cell_viability
Value
reduced cytotoxicity compared to free peptide
Target
MRC-5
Assay
Not reported by source
Source publication

Local peptide labels such as P1, PEP1, or peptide 1 are grouped only within this paper and are not assumed to represent the same molecule across publications.