AntimicrobialAntibacterialPositive observation
Record detail Table 2: D-CAP-18_31 MIC 2 mg/L against P. aeruginosa strain 121007
- Measure
- MIC
- Value
- 2 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
Source publication
In Vitro and In Vivo Characterization of Novel Cathelicidin-Based Peptides with Antimicrobial Activity Against Pseudomonas aeruginosa
Antibiotics · 2025
- Sequence status
- reported
- Standardization
- Sequence ready
- Source location
- table
- Activity records
- 22
Sequence evidence
Reported molecular identity
GLRKRLRKFRNKIKEKLKKIGQKIQGLLPKL
Table 2: D-CAP-18_31 sequence Glrkrlrkfrnkikeklkkigqkiqgllpkl (lowercase = D-amino acids)
Resolved peptide links
Experimental observations
Records linked to this mention
AntimicrobialAntibacterialPositive observation
Record detail Table 2: D-CAP-18_31 MIC 0.25 mg/L against P. aeruginosa ATCC 121110
- Measure
- MIC
- Value
- 0.25 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 3: D-CAP-18_31 MIC50 4 mg/L against P. aeruginosa strain panel
- Measure
- other
- Value
- 4 (MIC_50)
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 3: D-CAP-18_31 MIC90 16 mg/L against P. aeruginosa strain panel
- Measure
- other
- Value
- 16 (MIC_90)
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
ToxicityHemolyticPositive observation
Record detail Table 4: D-CAP-18_31 hemolysis IC50 108.44 uM against human erythrocytes
- Measure
- other
- Value
- 108.44 µM
- Target
- Homo sapiens
- Assay
- Not reported by source
ToxicityCytotoxicPositive observation
Record detail Table 4: D-CAP-18_31 cytotoxicity IC50 12.32 uM against A549 cells
- Measure
- other
- Value
- 12.32 µM
- Target
- A549
- Assay
- Not reported by source
ToxicityCytotoxicPositive observation
Record detail Section 3: D-CAP-18_31 IC50 6.16 uM against HeLa cells (mentioned in discussion)
- Measure
- other
- Value
- 6.16 µM
- Target
- HeLa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 0.25 mg/L against P. aeruginosa 12-1110 S1
- Measure
- MIC
- Value
- 0.25 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 0.5 mg/L against P. aeruginosa 21-0505 S2
- Measure
- MIC
- Value
- 0.5 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 4 mg/L against P. aeruginosa 21-0308 R2
- Measure
- MIC
- Value
- 4 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 4 mg/L against P. aeruginosa 15-0803 S3
- Measure
- MIC
- Value
- 4 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 0.5 mg/L against P. aeruginosa 15-0307 S4
- Measure
- MIC
- Value
- 0.5 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 0.5 mg/L against P. aeruginosa 21-0410 S5
- Measure
- MIC
- Value
- 0.5 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 4 mg/L against P. aeruginosa 16359347-2 R3
- Measure
- MIC
- Value
- 4 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 2 mg/L against P. aeruginosa 36a
- Measure
- MIC
- Value
- 2 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 4 mg/L against P. aeruginosa 38a
- Measure
- MIC
- Value
- 4 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 4 mg/L against P. aeruginosa 27853
- Measure
- MIC
- Value
- 4 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 16 mg/L against P. aeruginosa C1
- Measure
- MIC
- Value
- 16 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 16 mg/L against P. aeruginosa C2
- Measure
- MIC
- Value
- 16 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 8 mg/L against P. aeruginosa C3
- Measure
- MIC
- Value
- 8 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 8 mg/L against P. aeruginosa C4
- Measure
- MIC
- Value
- 8 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table A1: D-CAP-18_31 MIC 4 mg/L against P. aeruginosa C5
- Measure
- MIC
- Value
- 4 other
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
Local peptide labels such as P1, PEP1, or peptide 1 are grouped only within this paper and are not assumed to represent the same molecule across publications.