AntimicrobialAntibacterialPositive observation
Record detail Table 2: S. aureus (KCTC 1621) MIC = 4 μM for BP100.
- Measure
- MIC
- Value
- 4.0 μM
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
Source publication
Enhanced Antibacterial, Anti-Inflammatory, and Antibiofilm Activities of Tryptophan-Substituted Peptides Derived from Cecropin A-Melittin Hybrid Peptide BP100
Molecules · 2024
- Sequence status
- reported
- Standardization
- Sequence ready
- Source location
- unknown
- Activity records
- 31
Sequence evidence
Reported molecular identity
KKLFKKILKYLNH
KKLFKKILKYL-NH2
Resolved peptide links
Experimental observations
Records linked to this mention
AntimicrobialAntibacterialPositive observation
Record detail Table 2: S. epidermidis (KCTC 1917) MIC = 4 μM for BP100.
- Measure
- MIC
- Value
- 4.0 μM
- Target
- Staphylococcus epidermidis
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 2: B. subtilis (KCTC 3068) MIC = 8 μM for BP100.
- Measure
- MIC
- Value
- 8.0 μM
- Target
- Bacillus subtilis
- Assay
- Not reported by source
AntimicrobialAnti-Gram+Positive observation
Record detail Table 2: MRSA (CCARM 3089) MIC = 32 μM for BP100.
- Measure
- MIC
- Value
- 32.0 μM
- Target
- Methicillin-resistant Staphylococcus aureus
- Assay
- Not reported by source
AntimicrobialAnti-Gram+Positive observation
Record detail Table 2: MRSA (CCARM 3090) MIC = 64 μM for BP100.
- Measure
- MIC
- Value
- 64.0 μM
- Target
- Methicillin-resistant Staphylococcus aureus
- Assay
- Not reported by source
AntimicrobialAnti-Gram-Positive observation
Record detail Table 2: E. coli (KCTC 1682) MIC = 4 μM for BP100.
- Measure
- MIC
- Value
- 4.0 μM
- Target
- Escherichia coli
- Assay
- Not reported by source
AntimicrobialAnti-Gram-Positive observation
Record detail Table 2: P. aeruginosa (KCTC 1637) MIC = 16 μM for BP100.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAnti-Gram-Positive observation
Record detail Table 2: S. typhimurium (KCTC 1926) MIC = 4 μM for BP100.
- Measure
- MIC
- Value
- 4.0 μM
- Target
- Salmonella typhimurium
- Assay
- Not reported by source
AntimicrobialAnti-Gram-Positive observation
Record detail Table 2: MDRPA (CCARM 2095) MIC = 32 μM for BP100.
- Measure
- MIC
- Value
- 32.0 μM
- Target
- Multidrug-resistant Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAnti-Gram-Positive observation
Record detail Table 2: MDRPA (CCARM 2109) MIC = 16 μM for BP100.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Multidrug-resistant Pseudomonas aeruginosa
- Assay
- Not reported by source
ToxicityHemolyticNegative / threshold
Record detail Table 2: HC10 >256 μM for BP100 (no detectable hemolysis at 256 μM).
- Measure
- other
- Value
- >256 (HC10)
- Target
- Ovis aries
- Assay
- Not reported by source
AntimicrobialAnti-BiofilmPositive observation
Record detail Table 3: BP100 MBIC50 = 4–8 μM against MDRPA.
- Measure
- other
- Value
- 4–8 (MBIC50)
- Target
- Multidrug-resistant Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAnti-BiofilmPositive observation
Record detail Table 3: BP100 MBIC90 = 8 μM against MDRPA.
- Measure
- other
- Value
- 8.0 μM (MBIC90)
- Target
- Multidrug-resistant Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAnti-BiofilmPositive observation
Record detail Table 3: BP100 MBEC50 = 16–32 μM against MDRPA.
- Measure
- other
- Value
- 16–32 (MBEC50)
- Target
- Multidrug-resistant Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAnti-BiofilmPositive observation
Record detail Table 3: BP100 MBEC90 = 32 μM against MDRPA.
- Measure
- other
- Value
- 32.0 μM (MBEC90)
- Target
- Multidrug-resistant Pseudomonas aeruginosa
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: E. coli control MIC = 4 μM for BP100.
- Measure
- MIC
- Value
- 4.0 μM
- Target
- Escherichia coli
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: E. coli MIC = 16 μM for BP100 in 150 mM NaCl.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Escherichia coli
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: E. coli MIC = 16 μM for BP100 in 4.5 mM KCl.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Escherichia coli
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: E. coli MIC = 16 μM for BP100 in 6 μM NH4Cl.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Escherichia coli
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: E. coli MIC = 16 μM for BP100 in 1 mM MgCl2.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Escherichia coli
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: E. coli MIC = 16 μM for BP100 in 2.5 mM CaCl2.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Escherichia coli
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: E. coli MIC = 16 μM for BP100 in 4 μM FeCl3.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Escherichia coli
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: E. coli MIC = 16 μM for BP100 in 10% human serum.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Escherichia coli
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: S. aureus control MIC = 4 μM for BP100.
- Measure
- MIC
- Value
- 4.0 μM
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: S. aureus MIC = 16 μM for BP100 in 150 mM NaCl.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: S. aureus MIC = 16 μM for BP100 in 4.5 mM KCl.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: S. aureus MIC = 16 μM for BP100 in 6 μM NH4Cl.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: S. aureus MIC = 16 μM for BP100 in 1 mM MgCl2.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: S. aureus MIC = 16 μM for BP100 in 2.5 mM CaCl2.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: S. aureus MIC = 16 μM for BP100 in 4 μM FeCl3.
- Measure
- MIC
- Value
- 16.0 μM
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Table 4: S. aureus MIC = 32 μM for BP100 in 10% human serum.
- Measure
- MIC
- Value
- 32.0 μM
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
Local peptide labels such as P1, PEP1, or peptide 1 are grouped only within this paper and are not assumed to represent the same molecule across publications.