Nutrients · 2023
Sequence evidence
YGLYPR
YGLYPR
Experimental observations
Compared with the original hexapeptide YR6, the IC50 values of the hexapeptides AGR6 and YGR6 decreased from 2.442 ± 0.0066 mmol/L to 2.339 ± 0.0047 mmol/L (p < 0.01) and 1.695 ± 0.0108 mmol/L (p < 0.01), respectively.
Furthermore, compared with the original hexapeptide YR6, the IC50 values of the hexapeptides AGR6 and YGR6 decreased from 0.844 ± 0.0020 mmol/L to 0.6065 ± 0.0147 mmol/L (p < 0.01) and 0.5929 ± 0.0050 mmol/L (p < 0.01), respectively.
Table 1: YR6 at 12.5 μg/mL, NO Inhibition Rate = 14.51 ± 0.15%.
Table 1: YR6 at 25 μg/mL, NO Inhibition Rate = 17.81 ± 0.34%.
Table 1: YR6 at 50 μg/mL, NO Inhibition Rate = 10.46 ± 0.09%.
Table 1: YR6 at 100 μg/mL, NO Inhibition Rate = 5.65 ± 0.37%.
Local peptide labels such as P1, PEP1, or peptide 1 are grouped only within this paper and are not assumed to represent the same molecule across publications.
