MetaADEDB 2.0 @ LMMD
Lofepramine
(SAPNXPWPAUFAJU-UHFFFAOYSA-N)
Structure
SMILES
CN(CC(=O)c1ccc(cc1)Cl)CCCN1c2ccccc2CCc2c1cccc2
Type(s)
Experimental
ATC code(s)
N06AA07
Molecular Formula:
C26H27ClN2O
Molecular Weight:
418.958
Log P:
5.8465
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
0
TPSA:
23.55
CAS Number(s):
23047-25-8
Synonym(s)
1.
Lofepramine
2.
Lopramine
3.
Deftan
4.
Feprapax
5.
Gamanil
6.
Gamonil
7.
Leo 640
8.
Lofepramine Hydrochloride
9.
Lomont
10.
Hydrochloride, Lofepramine
External Link(s)
MeSHD008127
PubChem Compound3947
BindingDB82437
ChEBI47782
CHEMBLCHEMBL87708
DrugBankDB13411
DrugCentral1592
IUPHAR/BPS Guide to PHARMACOLOGY7551
KEGGdr:D08140
Therapeutic Target DatabaseD0K3MC
ZINC1542929
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Agitated depressionOFFSIDES
2AmnesiaOFFSIDES
3AngioedemaOFFSIDES
4AnhedoniaOFFSIDES
5AnhidrosisOFFSIDES
6AnorexiaOFFSIDES
7Anticholinergic SyndromeOFFSIDES
8AnxietyOFFSIDES
9ApathyOFFSIDES
10AppendicitisOFFSIDES
11Biliary dilatationOFFSIDES
12Bipolar DisorderOFFSIDES
13Blurred visionOFFSIDES
14BronchopneumoniaOFFSIDES
15Completed SuicideOFFSIDES
16ConfabulationOFFSIDES
17CryingOFFSIDES
18Depressed moodOFFSIDES
19Device migrationOFFSIDES
20Drug exposure during pregnancyOFFSIDES
21Drug exposure via breast milkOFFSIDES
22Dyspnoea exacerbatedOFFSIDES
23Dysthymic DisorderOFFSIDES
24Emotional disorderOFFSIDES
25Emotional distressOFFSIDES
26Erythema Nodosum15701135CTD
27Eye muscle operationOFFSIDES
28FatigueOFFSIDES
29Feeling abnormalOFFSIDES
30Feelings of worthlessnessOFFSIDES
31FormicationOFFSIDES
32Gamma-Glutamyltransferase IncreasedOFFSIDES
33HELLP SyndromeOFFSIDES
34HypomaniaOFFSIDES
35ImmobileOFFSIDES
36IncontinenceOFFSIDES
37Injection site cellulitisOFFSIDES
38Intention tremorOFFSIDES
39Intentional self-injuryOFFSIDES
40Intestinal PerforationOFFSIDES
41LethargyOFFSIDES
42Lysosomal Storage Diseases28551711CTD
43MegacolonOFFSIDES
44NauseaOFFSIDES
45Neuroleptic Malignant SyndromeOFFSIDES
46Noonan SyndromeOFFSIDES
47OverdoseOFFSIDES
48PallorOFFSIDES
49Personality ChangeOFFSIDES
50Pharyngolaryngeal PainOFFSIDES
51PolyhydramniosOFFSIDES
52Poor quality sleepOFFSIDES
53PriapismOFFSIDES
54PsoriasisOFFSIDES
55Psychiatric symptomOFFSIDES
56ThyroiditisOFFSIDES
57Unevaluable eventOFFSIDES
58Unresponsive to stimuliOFFSIDES
59Visual disturbanceOFFSIDES
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