Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 997
Aptamer sequence: ATCCGTCACACCTGCTCTCCCCGGCGTCCGTTTATTAGCAGACTTTGGCGGAATTGGTGTTGGCTCCCGTAT
Target unique ID: Other-27
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_906 | seqU2 | Other | β-Casomorphin-7 (BCM-7) | 41.85 nM | 20 mM Tris HCl, 10.0 mM EDTA, 3.5 M Urea, and 0.02% Tween 20, pH 8.0 | 25712869 |
Structure information of aptamer
| Aptamer Sequence: | ATCCGTCACACCTGCTCTCCCCGGCGTCCGTTTATTAGCAGACTTTGGCGGAATTGGTGTTGGCTCCCGTAT |
| The optimal secondary structure in dot-bracket notation: | ....((((((((.....(((((((.(((.(((....))).))).)))).)))...)))).))))........ |
| The centroid secondary structure in dot-bracket notation: | ....((((((((.....(((((((.(((.(((....))).))).)))).)))...))))).)))........ |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_906 | Description | seqU2 |
| Aptamer chemistry | DNA | Length | 72 nt |
| GC content | 55.6% | Molecular weight | 22,050.06 Da |
| Molarity of 1 μg/μl solution | 45.35 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Targeted binding |
| Sequence | ATCCGTCACACCTGCTCTCCCCGGCGTCCGTTTATTAGCAGACTTTGGCGGAATTGGTGTTGGCTCCCGTAT | ||
| Applications | Sensing of β?Casomorphin?7 | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-27 | Name | β-Casomorphin-7 (BCM-7) |
Activity data
 |
Interaction ID | 997 |
| Target type | Other | |
| Target unique ID | Other-27 | |
| Activity | 41.85 nM | |
| Binding Conditions/Buffer | 20 mM Tris HCl, 10.0 mM EDTA, 3.5 M Urea, and 0.02% Tween 20, pH 8.0 |
|
| Assay | ELASA for BCM-7. The extent of displacement of the BCM-7 peroxidase conjugate by BCM-7, BCM-5, BCM-9A1, and BCM-9A2 at fixed concentration |
|
| PubMed ID | 25712869 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_826 | DNA | ATCCGTCACACCTGCTCTGCACGGGCTCAGTTTGGCTTTGTATCCTAAGAGGGATGGTGTTGGCTCCCGTAT | |
| Apta_529 | DNA | ATCCGTCACACCTGCTCTACACTCCGCACGATCTTTTTTAGAACGCGTACCCGTTGGTGTTGGCTCCCGTAT | |
| Apta_1050 | DNA | ATCCGTCACACCTGCTCTCACGTCCGTCAACCAGATTGATACTTTATCTTGTTGTGGTGTTGGCTCCCGTAT | |
| Apta_1051 | DNA | ATCCGTCACACCTGCTCTATACACATTGTGTTTACTCCCAGTTTTTTAGACTTATGGTGTTGGCTCCCGTAT | |
| Apta_530 | DNA | ATCCGTCACACCTGCTCTGTGTACGCCCGTATTTACGTTCCTAGCAATTGCTATGTGGTGTTGGCTCCCGTAT | |
| Apta_524 | DNA | ATCCGTCACACCTGCTCTGGCATTAGTATTCCATAGCCGGCCAAGTCTATGTAGTGGTGTTGGCTCCCGTAT | |
| Apta_536 | DNA | ATCCGTCACACCTGCTCTCGAATAGAGTACTCGATACTGACTTTATTTACCGTCTGGTGTTGGCTCCCGTAT | |
| Apta_1052 | DNA | ATCCGTCACACCTGCTCTATTCCTCTGTTGAAGAACCACTTCCGGAAATAAGAGTGGTGTTGGCTCCCGTAT | |
| Apta_511 | DNA | ATCCGTCACACCTGCTCTCAGGGGATCACATTCTTGACGGTGTGATACAGTGCCTGGTGTTGGCTCCCGTAT | |
| Apta_532 | DNA | ATCCGTCACACCTGCTCTAACTTACACATAATTCTAGGTTACATCTTGCTCATATGGTGTTGGCTCCCGTAT | |
| Apta_535 | DNA | ATCCGTCACACCTGCTCTTGGGGTTATTACTCGTGAGATTGGGAATAGGTTACATGGTGTTGGCTCCCGTAT | |
| Apta_537 | DNA | ATCCGTCACACCTGCTCTCCTCGAACTAGTTAGACCCTCCTCCAAGTCAACTTGTGGTGTTGGCTCCCGTAT | |
| Apta_899 | DNA | ATCCGTCACACCTGCTCTCGAATAGAGTATTCGATACTGACTTTATTTACCGTCTGGTGTTGGCTCCCGTAT | |
| Apta_523 | DNA | ATCCGTCACACCTGCTCTGACGCTGGGGTCGACCCGGAGAAATGCATTCCCCTGTGGTGTTGGCTCCCGTAT | |
| Apta_525 | DNA | ATCCGTCACACCTGCTCTCAATCTGAAATATTGCAAGCAGTGCTCACAATTTGTTGGTGTTGGCTCCCGTAT | |
| Apta_534 | DNA | ATCCGTCACACCTGCTCTTGTAGGGTTCCCACCCAATTCAGTTCCGTTAAACCATGGTGTTGGCTCCCGTAT | |
| Apta_534 | DNA | ATCCGTCACACCTGCTCTTGTAGGGTTCCCACCCAATTCAGTTCCGTTAAACCATGGTGTTGGCTCCCGTAT | |
| Apta_815 | DNA | CATCCGTCACACCTGCTCTGGCCACTAACATGGGGACCAGGTGGTGTTGGCTCCCGTATC | |
| Apta_741 | DNA | ATCGTCTGCTCCGTCCAATAGCCTCACCCTGCATAATTTATAGACTACACTTAGGAATCGCTGCATTTGGTGTGAGGTCGTGC | |
| Apta_740 | DNA | ATCGTCTGCTCCGTCCAATAAACCTGCATAATTTATAAGTCTAGACTGCTGCATTTGGTGTGAGGTCGTGC |
DEV TOOL
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