Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 981
Aptamer sequence: GGAGACCGTACCATCTGTTCGTGGAAGCGCTTTGCTCGTCCATTAGCCTTGTGCTCGTGC
Target unique ID: Other-25
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_891 Aptamer clone37 Other Escherichia coli (ETEC) K88 25 nM 20 mmol/L HEPES, 1 mmol/L MgCl2, 1 mmol/L CaCl2 and 120 mmol/L KCl 21627466
Structure information of aptamer
Aptamer Sequence: GGAGACCGTACCATCTGTTCGTGGAAGCGCTTTGCTCGTCCATTAGCCTTGTGCTCGTGC
The optimal secondary structure in dot-bracket notation: .......((((.....(((.((((((((.....)))..))))).)))...))))......
The centroid secondary structure in dot-bracket notation: .......((((.....(((.((((((((.....)))..))))).)))...))))......
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_891 Description Aptamer clone37
Aptamer chemistry DNA Length 60 nt
GC content 56.7% Molecular weight 18,431.76 Da
Molarity of 1 μg/μl solution 54.25 μM Number of G-quadruplexes No QGRS found
G-Score N/A Function Target detection
Sequence GGAGACCGTACCATCTGTTCGTGGAAGCGCTTTGCTCGTCCATTAGCCTTGTGCTCGTGC
Applications Detection of Escherichia coli K88
Target information
Type Detail Type Detail
Target ID Other-25 Name Escherichia coli (ETEC) K88
Activity data

No relevant experimental diagram

 Interaction ID 981
Target type Other
Target unique ID Other-25
Activity 25 nM
Binding Conditions/Buffer

20 mmol/L HEPES, 1 mmol/L MgCl2, 1 mmol/L CaCl2 and 120 mmol/L KCl
Assay

N/A
PubMed ID 21627466
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_589 DNA GGGAATTCGAGCTCGGTACCATCTGTGTAAGGGGTAAGGGGTGGGGGTGGGTACGTCTAGCTGCAGGCATGCAAGCTTGG 56.25%
Apta_589 DNA GGGAATTCGAGCTCGGTACCATCTGTGTAAGGGGTAAGGGGTGGGGGTGGGTACGTCTAGCTGCAGGCATGCAAGCTTGG 56.25%
Apta_1212 DNA CTGTTCTCGGTCGCGACCTATCTGGTCGTCGCCGCGCTCGTGTTCGGAACGCTCATCGCGTTCGGGCTCGGCG 56.16%
Apta_235 DNA AGCAGCACAGAGGTCAGATGTGGTTCGATGCTGCAAGGTGTTGTCATTTGGCATATGTTACCTATGCGTGCTACCGTGAA 55.00%
Apta_890 DNA GGCGGCCGTGAAATTTGCCAAATGCCGTCTTGGCTTTCGCCCAATGTATCCTGGGTGTTC 55.00%
Apta_1162 DNA AGAGGCTACAGCGATAAGTCGACATTGCTGACCGTACCTAGTAATACGT 55.00%
Apta_1216 DNA AGCGTCCTCTGCATAGTGATTTACGCTATGTGTACAGTGC 55.00%
Apta_553 DNA TGTACCGTCTGAGCGATTCGTACGAACGGCTTTGTACTGTTTGCACTGGCGGATTTAGCCAGTCAGTGTTAAGGAGTGC 54.43%
Apta_554 DNA TGTACCGTCTGAGCGATTCGTACCATTAGTGGGTGCTCCTTACCTGATGGTCATCTAGCCAGTCAGTGTTAAGGAGTGC 54.43%
Apta_732 DNA AAGGAGCAGCGTGGAGGATAGCTGTCATCGGCTTATGTGCTTTCCAGGGTCCGTGCTGTCCGTTGTTAGGGTGTGTCGTCGTGGT 54.12%
Apta_737 DNA ATCGTCTGCTCCGTCCAATAGTGCATTGAAACTTCTGCATCCTCGTTTGGTGTGAGGTCGTGC 53.97%
Apta_99 DNA AGCAGCACAGAGGTCAGATGTCGGGCGGTTCGGGACCTTGCTGCGACATATGCGTATTATCCTATGCGTGCTACCGTGAA 53.75%
Apta_101 DNA AGCAGCACAGAGGTCAGATGTGTTAGGCTGGGACACGTATTACACTTACCGTAAATATTTCCTATGCGTGCTACCGTGAA 53.75%
Apta_110 DNA AGCAGCACAGAGGTCAGATGGTTAGGAAGGTGAATAGGTACGACTGCAGGTCTATCGCAGCCTATGCGTGCTACCGTGAA 53.75%
Apta_99 DNA AGCAGCACAGAGGTCAGATGTCGGGCGGTTCGGGACCTTGCTGCGACATATGCGTATTATCCTATGCGTGCTACCGTGAA 53.75%
Apta_101 DNA AGCAGCACAGAGGTCAGATGTGTTAGGCTGGGACACGTATTACACTTACCGTAAATATTTCCTATGCGTGCTACCGTGAA 53.75%
Apta_110 DNA AGCAGCACAGAGGTCAGATGGTTAGGAAGGTGAATAGGTACGACTGCAGGTCTATCGCAGCCTATGCGTGCTACCGTGAA 53.75%
Apta_234 DNA AGCAGCACAGAGGTCAGATGAAATTTTGCACTTACTTGACGTTTCCTCGATAGCCACAAGCCTATGCGTGCTACCGTGAA 53.75%
Apta_555 DNA TGTACCGTCTGAGCGATTCGTACGGATTGGGTTTGCACTTTACCTGCGGTGCATCGCAGCCAGTCAGTGTTAAGGAGTGC 53.75%
Apta_67 DNA AGATGCCTGTCGAGCATGCTGTTGTGGTAGGGTTAGGGATGGTAGCGGTTGTAGCTAAACTGCTTTGTCGACGGG 53.33%

ABOUT

AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

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