Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 936
Aptamer sequence: CACCAGTGTGTTGAGGTTTGAGCACACTGATAGAGTGTCA
Target unique ID: Other-2
| Aptamer ID | Aptamer descriptor | Target chemistry | Target name | Affinity | Binding Conditions/Buffer | PubMed ID |
|---|---|---|---|---|---|---|
| Apta_850 | SMV-19 | Other | Human Norovirus | 191 nM | 500 ml of binding buffer [consisting of phosphate buffered saline (pH 7.1) supplemented with 100 mg/L CaCl2, 100 mg/L MgCl2 and 0.05% Tween 20] at Room Temperature | 25192421 |
Structure information of aptamer
| Aptamer Sequence: | CACCAGTGTGTTGAGGTTTGAGCACACTGATAGAGTGTCA |
| The optimal secondary structure in dot-bracket notation: | ...(((((((((........)))))))))........... |
| The centroid secondary structure in dot-bracket notation: | ...(((((((((........)))))))))........... |
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Aptamer ID | Apta_850 | Description | SMV-19 |
| Aptamer chemistry | DNA | Length | 40 nt |
| GC content | 47.5% | Molecular weight | 12,390.97 Da |
| Molarity of 1 μg/μl solution | 80.70 μM | Number of G-quadruplexes | No QGRS found |
| G-Score | N/A | Function | Target detection |
| Sequence | CACCAGTGTGTTGAGGTTTGAGCACACTGATAGAGTGTCA | ||
| Applications | HuNoV capture and detection assays | ||
Target information
| Type | Detail | Type | Detail |
|---|---|---|---|
| Target ID | Other-2 | Name | Human Norovirus |
Activity data
 |
Interaction ID | 936 |
| Target type | Other | |
| Target unique ID | Other-2 | |
| Activity | 191 nM | |
| Binding Conditions/Buffer | 500 ml of binding buffer [consisting of phosphate buffered saline (pH 7.1) supplemented with 100 mg/L CaCl2, 100 mg/L MgCl2 and 0.05% Tween 20] at Room Temperature |
|
| Assay | Equilibrium dissociation curves for select aptamers |
|
| PubMed ID | 25192421 |
Similar aptamers
| Aptamer ID | Aptamer chemistry | Sequence | Similarity |
|---|---|---|---|
| Apta_66 | DNA | TACCGTGGTAGGGAAGGTTGGAGTGTA | |
| Apta_851 | DNA | CCATGTTTTGTAGGTGTAATAGGTCATGTTAGGGTTTCTG | |
| Apta_1149 | DNA | ATCATGGTGGGTATCGGCACTCGTTGGTTGAT | |
| Apta_1081 | DNA | CTTACGACTGTGGTCGGGTGGTGGGCCTCTAGAGGGGTGTCGTAAG | |
| Apta_449 | DNA | CGCACTATGTTTTACGAGCCGTTTCCTCGGCAGATAGTAAGTGCG | |
| Apta_749 | DNA | GATCGGTGGGTGGGGGGGTTGGAGATCATCCTCAGGGATTACGTC | |
| Apta_63 | DNA | GACCCGTGGTAGGGTAGGATGGGGTGGTC | |
| Apta_65 | DNA | CTACCGTGGTAGGGAAGGTTGGAGTGTAG | |
| Apta_339 | DNA | CACAGGCTACGGCACGTAGAGCATCACCATGATCCTGTGT | |
| Apta_492 | DNA | GCGAGGTGTTCGAGAGTTAGGGGCGACATGACCAAACGTT | |
| Apta_964 | DNA | CACGAGAGGGGTGAGGTGTCGTATTAGAGGGAAGCTCCAA | |
| Apta_965 | DNA | CACGGCATGTGTGGCCGGATGCCTATATCGGTCGACTGCA | |
| Apta_395 | DNA | AATCCACGTATCGACTAGCTCAAACCAGCCTGATAGAGCCATTCGCTTTA | |
| Apta_968 | DNA | TAACACGACAGACGTTCGGAGGTCGAACCCTGACAGCGTGGGC | |
| Apta_930 | DNA | TTGCACTATGTTTTAGCTAGGGTTCCCTCCGGAGATAGTAAGTGCAA | |
| Apta_143 | DNA | GGTGCGGTTCGTGCGGTTGTAGTACTCGTGGCCGATAGAGGTAGTTTCG | |
| Apta_597 | DNA | TACTGGGCTGGGCTTGGATTAGATCACAGTGGAACATACAGGACACACG | |
| Apta_49 | DNA | CTTCCATGTTGAGGCGTTTATACCAGTTATCATCGGACTA | |
| Apta_158 | DNA | CACAGGCTACGGCACGTAGAGCATCACCATGATCCTGTG | |
| Apta_183 | DNA | TAGCACTGTGCGGCGCGTATTGTTCTAATCTGATTACATT |
DEV TOOL
 |
 |
 |
 |