Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 605
Aptamer sequence: CCGTAACCCTGCGGGGGGGGGAGAAGGCAATGGGGGACAACTCGCCGGTAGCCATCCATAT
Target unique ID: 6857375
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_572 Chi No. 46 (61) Molecule N-[(2R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide N/A 100 mM NaCl, 100 mM KCl, 5 mM MgCl2, 50 mM Tris-acetate (pH 8.0) 10743940
Structure information of aptamer
Aptamer Sequence: CCGTAACCCTGCGGGGGGGGGAGAAGGCAATGGGGGACAACTCGCCGGTAGCCATCCATAT
The optimal secondary structure in dot-bracket notation: ......((((....)))).(((...(((.((.((.((....)).)).)).))).)))....
The centroid secondary structure in dot-bracket notation: ...................(((...(((.((.((.((....)).)).)).))).)))....
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_572 Description Chi No. 46 (61)
Aptamer chemistry DNA Length 61 nt
GC content 63.9% Molecular weight 18,955.12 Da
Molarity of 1 μg/μl solution 52.76 μM Number of G-quadruplexes 2
G-Score 21 Function Aptasensor
Sequence CCGTAACCCTGCGGGGGGGGGAGAAGGCAATGGGGGACAACTCGCCGGTAGCCATCCATAT
Applications Recognition of chitin
Target information
Type Detail Type Detail
PubChem ID 6857375 Molecular name N-[(2R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
Molecular formula C8H15NO6 Molecular weight 221.21
IUPAC name N-[(2R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide InChIKey OVRNDRQMDRJTHS-WTZNIHQSSA-N
LogP -3.078 Topological polar surface area 119.25
Hydrogen bond acceptor 6 Hydrogen bond donor 5

Synonym(s):
Chitin, Practical Grade; N-[(2R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide; 1398-61-4; Chitin from shrimp shells; SCHEMBL8656145; Chitin from shrimp shells, practical grade, powder; Chitin from shrimp shells, Vetec(TM) reagent grade; Chitin from shrimp shells, practical grade, coarse flakes; Chitin from shrimp shells, BioReagent, suitable for analysis of chitinase, purified powder

Activity data

No relevant experimental diagram

 Interaction ID 605
Target type Molecule
Target unique ID 6857375
Activity N/A
Binding Conditions/Buffer

100 mM NaCl, 100 mM KCl, 5 mM MgCl2, 50 mM Tris-acetate (pH 8.0)
Assay

N/A
PubMed ID 10743940
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_708 DNA CGTACGGAATTCGCTAGCGGGCGGGGGTGCTGGGGGAATGGAGTGCTGCGTGCTGCGGGGATCCGAGCTCCACGTG 57.89%
Apta_485 DNA TGTCGTTGGGGGGGTAGGGAAGGGTGAAACGACAAGCCAGAAGTT 55.74%
Apta_511 DNA ATCCGTCACACCTGCTCTCAGGGGATCACATTCTTGACGGTGTGATACAGTGCCTGGTGTTGGCTCCCGTAT 55.56%
Apta_1090 DNA ATCCAGAGTGACGCAGCAGGGCTTGGGTTGGGAATAAGGATGTGGGAGGCGGCGAACATGGACACGGTGGCTTAGT 53.95%
Apta_524 DNA ATCCGTCACACCTGCTCTGGCATTAGTATTCCATAGCCGGCCAAGTCTATGTAGTGGTGTTGGCTCCCGTAT 52.78%
Apta_535 DNA ATCCGTCACACCTGCTCTTGGGGTTATTACTCGTGAGATTGGGAATAGGTTACATGGTGTTGGCTCCCGTAT 52.78%
Apta_1291 DNA CGTACGGAATTCGCTAGCCCCCCGGCAGGCCACGGCTTGGGTTGGTCCCACTGCGCGTGGATCCGAGCTCCACGTG 52.63%
Apta_1011 DNA GCTGTGTGACTCCTGCAATGGTAGCGGGTAGGGGAGGGAGGGTGAATGGAGGATGTTCATGGCAGCTGTATCTTGTCTCC 52.50%
Apta_282 DNA ATCCATGGGGCGGAGATGAGGGGGAGGAGGGCGGGTACCCGGTTGAT 52.46%
Apta_488 DNA CGACCAGGGTGGGAGGGGGACGGGCTGGCGGCGCGCGGTAATG 52.46%
Apta_1080 DNA CTTACGACCCAGGGGGGTGGACAGGCGGGGGTTAGGGGGGTCGTAAG 52.46%
Apta_465 DNA AGCTGACACAGCAGGTTGGTGGGGGTGGCTTCCAGTTGGGTTGACAATACGTAGGGACACGAAGTCCAACCACGAGTCGAGCAATCTCGAAAT 51.61%
Apta_1116 DNA CGTACGGAATTCGCTAGCCGGGGTGGGAACCAGTCTTGCGCGGGTGACGGATCCGAGCTCCACGTG 51.52%
Apta_45 DNA CGGGTGGGAGTTGTGGGGGGGGGTGGGAGGGTTCTTTGTTTGATCTTTCTCGCTGCCTGGCCCTAGAGTG 51.43%
Apta_523 DNA ATCCGTCACACCTGCTCTGACGCTGGGGTCGACCCGGAGAAATGCATTCCCCTGTGGTGTTGGCTCCCGTAT 51.39%
Apta_525 DNA ATCCGTCACACCTGCTCTCAATCTGAAATATTGCAAGCAGTGCTCACAATTTGTTGGTGTTGGCTCCCGTAT 51.39%
Apta_514 DNA ACTCAGCACGCGTGTAGGGAAAACCAACCGCCCACAAGCTGCATGCAACG 50.82%
Apta_619 DNA CCAACTTGGGCGGAGGGCTAACGGTGGGGGGATATTATGAGGGGTGGAGGTATTAACCATT 50.82%
Apta_666 DNA TCGACCTCGCGCGAGGAGGGTGGAGGGTCGTAGAGCGCGTA 50.82%
Apta_831 DNA CCGCCCAGCGGGGGTAGGGCCGGACGTAGGAGGAGCTGCG 50.82%

ABOUT

AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

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