Aptamer-target interaction descriptor
Aptamer-target interaction information
Interaction ID: 1292
Aptamer sequence: GGCGATAGGCAGTGTTGCGGGGTCGGAGAGCGAGGTAATAGCGTGTATGGGTGCTGTGTG
Target unique ID: 5353447
Aptamer ID Aptamer descriptor Target chemistry Target name Affinity Binding Conditions/Buffer PubMed ID
Apta_1230 BT 3 Molecule Brevetoxin 2 278 nM 50 mM Tris, pH 7.5, and 10 mM MgCl2 25725463
Structure information of aptamer
Aptamer Sequence: GGCGATAGGCAGTGTTGCGGGGTCGGAGAGCGAGGTAATAGCGTGTATGGGTGCTGTGTG
The optimal secondary structure in dot-bracket notation: (((((((.((..((((((...((......))...))))))..)).)))...)))).....
The centroid secondary structure in dot-bracket notation: ((((.((.((..((((((.....((.....))..))))))..)).))....)))).....
The MFE structure
The Centroid structure
The mountain plot representation
Aptamer information
Type Detail Type Detail
Aptamer ID Apta_1230 Description BT 3
Aptamer chemistry DNA Length 60 nt
GC content 60.0% Molecular weight 18,900.05 Da
Molarity of 1 μg/μl solution 52.91 μM Number of G-quadruplexes 2
G-Score 17 Function Aptasensor
Sequence GGCGATAGGCAGTGTTGCGGGGTCGGAGAGCGAGGTAATAGCGTGTATGGGTGCTGTGTG
Applications Detection of BTX-2 in food samples
Target information
Type Detail Type Detail
PubChem ID 5353447 Molecular name Brevetoxin 2
Molecular formula C50H70O14 Molecular weight 895.1
IUPAC name 2-[[(21Z)-12-hydroxy-1,3,11,24,31,41,44-heptamethyl-39-oxo-2,6,10,15,19,25,29,34,38,43,47-undecaoxaundecacyclo[26.22.0.03,26.05,24.07,20.09,18.011,16.030,48.033,46.035,44.037,42]pentaconta-21,40-dien-14-yl]methyl]prop-2-enal InChIKey LYTCVQQGCSNFJU-KTKRTIGZSA-N
LogP 5.472 Topological polar surface area 155.9
Hydrogen bond acceptor 14 Hydrogen bond donor 1

Synonym(s):
Brevetoxin 2; brevetoxin pbtx-2; 79580-28-2; Brevetoxin T 34; 2-[[(21Z)-12-hydroxy-1,3,11,24,31,41,44-heptamethyl-39-oxo-2,6,10,15,19,25,29,34,38,43,47-undecaoxaundecacyclo[26.22.0.03,26.05,24.07,20.09,18.011,16.030,48.033,46.035,44.037,42]pentaconta-21,40-dien-14-yl]methyl]prop-2-enal; Brevetoxin PbTx 2; GB 2 toxin; T-34 toxin; GB 2 (Gymnodinium); Toxin T-34; T 4-7 toxin; Ptychodiscus brevis toxin 2; GB 2; T 4-7

Activity data

No relevant experimental diagram

 Interaction ID 1292
Target type Molecule
Target unique ID 5353447
Activity 278 nM
Binding Conditions/Buffer

50 mM Tris, pH 7.5, and 10 mM MgCl2
Assay

N/A
PubMed ID 25725463
Similar aptamers
Aptamer ID Aptamer chemistry Sequence Similarity
Apta_748 DNA AGCTTGAGGGTGGGCGGGTGGACGCGGTAGTGGTATATAGGTCGG 60.00%
Apta_223 DNA CATTGAGATAGCTAGTTGTAGCTGCGTCATAGGCTGGGTTGGGTCTAGTGGTTGGGTGTG 58.33%
Apta_755 DNA GGGGAGGGAGACACAGTCATGGAGCAGTTATTAGGGTGTACCGGGTGTAGT 58.33%
Apta_109 DNA AGCAGCACAGAGGTCAGATGTGCGACCACCTGGATAGACGAGGGTAGTAAGGAGTGTGTTCCTATGCGTGCTACCGTGA 58.23%
Apta_109 DNA AGCAGCACAGAGGTCAGATGTGCGACCACCTGGATAGACGAGGGTAGTAAGGAGTGTGTTCCTATGCGTGCTACCGTGA 58.23%
Apta_110 DNA AGCAGCACAGAGGTCAGATGGTTAGGAAGGTGAATAGGTACGACTGCAGGTCTATCGCAGCCTATGCGTGCTACCGTGAA 57.50%
Apta_110 DNA AGCAGCACAGAGGTCAGATGGTTAGGAAGGTGAATAGGTACGACTGCAGGTCTATCGCAGCCTATGCGTGCTACCGTGAA 57.50%
Apta_1011 DNA GCTGTGTGACTCCTGCAATGGTAGCGGGTAGGGGAGGGAGGGTGAATGGAGGATGTTCATGGCAGCTGTATCTTGTCTCC 57.50%
Apta_148 DNA CCGTAGGTTCGGGGTCGGAGTGGTCCGGAAGGTGGCGTGG 56.67%
Apta_834 DNA CGCAATACCAAAGTGGCGAGAGCGCTGTCTTGAGTGAGTGGTTGG 56.67%
Apta_882 DNA AATAGTCTGGTTCGGTGCTTGGTGCGATGTGTTAGTCAGACTCTTGTGTG 56.67%
Apta_1259 DNA GGCGCGGCATGGTGTGGACTCCAGGCGGTAGGGATGTCGT 56.67%
Apta_99 DNA AGCAGCACAGAGGTCAGATGTCGGGCGGTTCGGGACCTTGCTGCGACATATGCGTATTATCCTATGCGTGCTACCGTGAA 56.25%
Apta_99 DNA AGCAGCACAGAGGTCAGATGTCGGGCGGTTCGGGACCTTGCTGCGACATATGCGTATTATCCTATGCGTGCTACCGTGAA 56.25%
Apta_232 DNA AGCAGCACAGAGGTCAGATGCTATGAGCAGATCCGATAGAAAGTTAATGCCCTAGAACATCCTATGCGTGCTACCGTGAA 56.25%
Apta_417 DNA GGCAGGAAGACAAACACCAGGTGAGGGAGACGACGCGAGTGTTAGATGGTAGCTGTTGGTCTGTGGTGCTGT 55.56%
Apta_228 DNA AGCAGCACAGAGGTCAGATGCGGCGCGGGGTCTTTTACAAATAGTTGTCCTAGCCACGCCTATGCGTGCTACCGTGAA 55.13%
Apta_50 DNA AGTGGCGAGGGGGGTAGGTAAAGTATCCTTAGTGTGTTG 55.00%
Apta_108 DNA AGCAGCACAGAGGTCAGATGCTTTGCCACGGCAACGTCCCAAAACTAATGGTAACTATACCCTATGCGTGCTACCGTGAA 55.00%
Apta_108 DNA AGCAGCACAGAGGTCAGATGCTTTGCCACGGCAACGTCCCAAAACTAATGGTAACTATACCCTATGCGTGCTACCGTGAA 55.00%

ABOUT

AptaDB is an online database we developed to integrate comprehensive information about aptamer.
The detail of this database is described here:

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