AptaDB: Result

Interaction ID: 1119

Aptamer sequence: CCTACGTTGGAGTGGGGTTTGCGCAGGCCGTTCTTTCCAA

Target unique ID: Other-53

Aptamer ID	Aptamer descriptor	Target chemistry	Target name	Affinity	Binding Conditions/Buffer	PubMed ID
Apta_1066	Apt_NDV05	Other	Newcastle disease virus (NDV)	47.9 nM	PBS (pH 7.2) with 150 mM NaCl and 5 mM MgCl2	32790805

Aptamer Sequence:	CCTACGTTGGAGTGGGGTTTGCGCAGGCCGTTCTTTCCAA
The optimal secondary structure in dot-bracket notation:	......((((((...(((((....))))).....))))))
The centroid secondary structure in dot-bracket notation:	.......(((((...((((......)))).....))))).

The MFE structure

The Centroid structure

The mountain plot representation

Type	Detail	Type	Detail
Aptamer ID	Apta_1066	Description	Apt_NDV05
Aptamer chemistry	DNA	Length	40 nt
GC content	57.5%	Molecular weight	12,325.88 Da
Molarity of 1 μg/μl solution	81.13 μM	Number of G-quadruplexes	No QGRS found
G-Score	N/A	Function	Target detection
Sequence	CCTACGTTGGAGTGGGGTTTGCGCAGGCCGTTCTTTCCAA
Applications	Detection of NDV in poultry samples

Type	Detail	Type	Detail
Target ID	Other-53	Name	Newcastle disease virus (NDV)

	Interaction ID	1119
	Target type	Other
	Target unique ID	Other-53
	Activity	47.9 nM
	Binding Conditions/Buffer	PBS (pH 7.2) with 150 mM NaCl and 5 mM MgCl2
	Assay	Highly specific aptamers against NDV
	PubMed ID	32790805

Aptamer ID	Aptamer chemistry	Sequence	Similarity
Apta_644	DNA	TCAATCTAACCATGCATGCAGTTTAGGCAGGATTCGTTATCGCAA	57.78%
Apta_124	DNA	GGTGGTGGGGGGGGTTGGTAGGGTGTCTTC	57.50%
Apta_239	DNA	CCCAGATTACTGTGGAGTGGTTGTCTGCGAATCCTTCGTCCACCCAATAG	56.00%
Apta_1063	DNA	AACTTATCGGAGCGTGATTTCCGTCTCGCCGCTTTCCTTT	55.00%
Apta_571	DNA	ACCTGCGATAGGTAGTTTGTTTCTGTTGCCCTAGCGTCCGTCGTAACAAGTCA	54.72%
Apta_782	DNA	AGGTGTGACTCGATCTGTGGGGGTTGGGGGGTGGTTTTTCGGAA	54.55%
Apta_1177	DNA	TCCTACTCGTGATATCGGTGTTTATGGTGTCTGTCTTCATGTAGGA	54.35%
Apta_930	DNA	TTGCACTATGTTTTAGCTAGGGTTCCCTCCGGAGATAGTAAGTGCAA	53.19%
Apta_1278	DNA	CCATGATTCAACTTTACTGGTCTTGTCTTGGCTAGTCGTGTGTCATTCCCTAAGG	52.73%
Apta_42	DNA	GCTGGTCTCTGCGGGTTGTTGCGCCGCGGCACCCTTGGCA	52.50%
Apta_364	DNA	TATGGTATGCTGTGTGGTATGGGGTGGCGTGCTCT	52.50%
Apta_392	DNA	GGATAGTTCGGTGGCTGTTCAGGGTCTCCTCCT	52.50%
Apta_552	DNA	CACCTGGGGGAGTATTGCGGAGGAAGGTTCCAGGTG	52.50%
Apta_915	DNA	ACTTCGGCTAGTTAGGGGGTAGTTTAGATCGTCTCTACAT	52.50%
Apta_1013	DNA	ATCACGTATGGGGGGCCGGCATGAGGGCCGCGCGTGACA	52.50%
Apta_1085	DNA	TGGGGTGGTGGTGTGGGTGGGGGTTTGTTC	52.50%
Apta_1149	DNA	ATCATGGTGGGTATCGGCACTCGTTGGTTGAT	52.50%
Apta_1241	DNA	GGTGTGGAGTGGTGTGTGTTGTTGTTTGTC	52.50%
Apta_1081	DNA	CTTACGACTGTGGTCGGGTGGTGGGCCTCTAGAGGGGTGTCGTAAG	52.17%
Apta_1087	DNA	CTTACGACTCAGGCATTTTGCCGGGTAACGAAGTTACTGTCGTAAG	52.17%

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