ProForma 2.0
Not calculated for this record
Back to Primary literature
Primary-literature peptidehigh evidence PepDiana evidence grade for a literature-derived identity; Medium indicates retained review flags, while High has no unresolved review flag.
PEPDIA-PLP-003436
DCMAC-VP
Aliases: DCANBP-VP, DCMAC-VP, Me6I2-BODIPY-VP, vasopressin
Normalized sequence
CYFQNCPRG
9 amino acids
Release PepDiana-V1-20260620
14
Activity records
1
Source papers
10
Positive
4
Negative / threshold
Cross-layer links
Related Integrated records
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.
Computed properties
physchem-20260620Molecular weight
Not calculated
Molecular formula
Not calculated
Theoretical pI
Not calculated
Net charge at pH 7
Not calculated
GRAVY
Not calculated
Instability index
Not calculated
Aromaticity
Not calculated
Topological polar surface area
Not calculated
cLogP
Not calculated
Hydrogen-bond donors
Not calculated
Hydrogen-bond acceptors
Not calculated
Rotatable bonds
Not calculated
Method: Not recorded
Tool: Not recorded
Calculated: Not recorded
Sequence representations
HELM 2.0
Not calculated for this record
Canonical SMILES
Not calculated for this record
Isomeric SMILES
Not calculated for this record
Paper-level observations
Experimental evidence grouped by activity
Other 14 records
PMC13206411
14 observationsOtherAnti-HIVPositive observation
Record detail Figure 5B; Table S2. VP positive control on hV1aR.
- Measure
- EC50
- Value
- Not reported
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVPositive observation
Record detail Figure 5C; Table S2. VP positive control on hV1bR.
- Measure
- EC50
- Value
- Not reported
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVPositive observation
Record detail Figure 5B; Table S2. DCMAC-VP 2 on hV1aR. Text: '565 → 3300-fold higher EC50 values than parent peptides'.
- Measure
- EC50
- Value
- =2
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVPositive observation
Record detail Figure 5C; Table S2. DCMAC-VP 2 on hV1bR. Text: '565 → 3300-fold higher EC50 values than parent peptides'.
- Measure
- EC50
- Value
- =2
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVNegative / threshold
Record detail Figure 5B; Table S2. DCANBP-VP 4 on hV1aR. Text: '>2,100-3,900-fold higher EC50 values compared to parent peptides'.
- Measure
- EC50
- Value
- >2,100
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVNegative / threshold
Record detail Figure 5C; Table S2. DCANBP-VP 4 on hV1bR. Text: '>2,100-3,900-fold higher EC50 values compared to parent peptides'.
- Measure
- EC50
- Value
- >2,100
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVPositive observation
Record detail Figure 5B; Table S2. Me6I2-BODIPY-VP 6 on hV1aR. Text: '3- to 9-fold rightward shift in EC50 compared to VP'.
- Measure
- EC50
- Value
- =6
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVPositive observation
Record detail Figure 5C; Table S2. Me6I2-BODIPY-VP 6 on hV1bR. Text: '3- to 9-fold rightward shift in EC50 compared to VP'.
- Measure
- EC50
- Value
- =6
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVPositive observation
Record detail Figure 5E; Table S3. DCMAC-VP 2* on hV1aR. Text: '340-fold increase in potency for hV1aR'.
- Measure
- EC50
- Value
- =2
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVPositive observation
Record detail Figure 5E; Table S3. DCANBP-VP 4* on hV1aR. Text: '385-fold increase in activity'.
- Measure
- EC50
- Value
- =4
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAnti-HIVPositive observation
Record detail Figure 5E; Table S3. Me6I2-BODIPY-VP 6* on hV1aR. Text: 'only a minor increase in activity (~2-fold)'.
- Measure
- EC50
- Value
- ~2
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAntibacterialNegative / threshold
Record detail Figure 5F. DCMAC-VP 2 at 100 nM on hOTR. Text: 'most caged photoprobes exhibited no activity at 100 nM'.
- Measure
- percent_inhibition
- Value
- na
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAntibacterialNegative / threshold
Record detail Figure 5F. DCANBP-VP 4 at 100 nM on hOTR. Text: 'most caged photoprobes exhibited no activity at 100 nM'.
- Measure
- percent_inhibition
- Value
- na
- Target
- Homo sapiens
- Assay
- Not reported by source
OtherAntibacterialPositive observation
Record detail Figure 5F. Me6I2-BODIPY-VP 6 at 100 nM on hOTR. Text: 'Me6I2-BODIPY-VP 6, with ~50% activation at hOTR'.
- Measure
- percent_inhibition
- Value
- ~50% activation
- Target
- Homo sapiens
- Assay
- Not reported by source
Citation and release provenance
Cite this identity as PepDiana record PEPDIA-PLP-003436, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.
Record updated: 2026-06-22T07:14:26.229247+00:00