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PEPDIA-INT-076514

Gold

(RW)3

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

RWRWRW

Indexed sequence6 aa

1RWRWRW

Length

Molecular weight

1045.22 Da

Formula

C51H68N18O7

Structure type

Linear

Synthesis

Synthetic

Chirality

Mixed

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic3

Membrane affinity proxy

Polar0

Solubility proxy

Charged3

Net charge proxy +3

Aromatic3

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

1045.2021 Da

Molecular formula

C51H68N18O7

Theoretical pI

Net charge at pH 7

2.7601

GRAVY

-2.7

Instability index

294.7333

Aromaticity

0.5

Topological polar surface area

441.89 Å²

cLogP

-0.2159

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

RWRWRW

HELM 2.0

validated simple linear

PEPTIDE1{R.W.R.W.R.W}$$$$V2.0

Canonical SMILES

validated

N=C(N)NCCCC(N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O

Isomeric SMILES

validated

N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-076514,
  title = {(RW)3},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-076514},
  note = {Accessed from local PepDiana development build}
}

APA-style note

(RW)3. (2026). PepDiana record PEPDIA-INT-076514. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-076514

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (89 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P076514_ACT_apd_0000	Antimicrobial	Anti-Gram+	Not available in the current structured import	Unknown	Not reported by source	AP04276apd / linked
CTPDB_P076514_ACT_avpdb_0002	Antiviral	General Antiviral	6.5 μM	Vaccinia	Plaque assay	AVPdb_AVP1531avpdb / unavailable
CTPDB_P076514_ACT_baamps_0003	Antimicrobial	Anti-Biofilm	Not available in the current structured import	Unknown	Not reported by source	EXP00233baamps / linked
CTPDB_P076514_ACT_baamps_0004	Antimicrobial	Anti-Biofilm	Not available in the current structured import	Unknown	Not reported by source	EXP00234baamps / linked
CTPDB_P076514_ACT_baamps_0005	Antimicrobial	Anti-Biofilm	Not available in the current structured import	Unknown	Not reported by source	EXP00244baamps / linked
CTPDB_P076514_ACT_camp_0006	Antimicrobial	Antifungal	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ11919camp / linked
CTPDB_P076514_ACT_camp_0007	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ13099camp / linked
CTPDB_P076514_ACT_camp_0008	Antimicrobial	Anti-Gram+	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ13099camp / linked
CTPDB_P076514_ACT_camp_0009	Antimicrobial	Anti-Gram-	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ13099camp / linked
CTPDB_P076514_ACT_camp_0010	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ17073camp / linked
CTPDB_P076514_ACT_dbaasp_0063	Antimicrobial	-	21 µM	Escherichia coli DSM 30083	Not reported by source	DBAASPS_17339_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0064	Antimicrobial	-	21 µM	Acinetobacter baumannii DSM 30007	Not reported by source	DBAASPS_17339_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0065	Antimicrobial	-	>100 µM	Pseudomonas aeruginosa DSM 50071	Not reported by source	DBAASPS_17339_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0066	Antimicrobial	-	1.3 µM	Bacillus subtilis DSM 402	Not reported by source	DBAASPS_17339_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0067	Antimicrobial	-	5.3 µM	Staphylococcus aureus DSM 20231	Not reported by source	DBAASPS_17339_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0068	Antimicrobial	-	5.3 µM	Staphylococcus aureus ATCC 43300	Not reported by source	DBAASPS_17339_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0069	Antimicrobial	-	2.1±0.7 µM	Staphylococcus aureus 133	Not reported by source	DBAASPS_17339_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0070	Antimicrobial	-	3.3±1.4 µM	Staphylococcus simulans 22	Not reported by source	DBAASPS_17339_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0071	Antimicrobial	-	4.2±1.4 µM	Staphylococcus aureus SG511	Not reported by source	DBAASPS_17339_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0072	Antimicrobial	-	3.8±1.8 µM	Bacillus subtilis DSM 402	Not reported by source	DBAASPS_17339_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0073	Antimicrobial	-	0.5±0.2 µM	Bacillus megaterium	Not reported by source	DBAASPS_17339_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0074	Antimicrobial	-	0.6±0.0 µM	Micrococcus luteus	Not reported by source	DBAASPS_17339_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0075	Antimicrobial	-	45 µM	Escherichia coli DSM 30083	Not reported by source	DBAASPS_17340_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0076	Antimicrobial	-	45 µM	Bacillus subtilis DSM 402	Not reported by source	DBAASPS_17340_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0077	Antimicrobial	-	90 µM	Escherichia coli DSM 30083	Not reported by source	DBAASPS_17341_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0078	Antimicrobial	-	90 µM	Bacillus subtilis DSM 402	Not reported by source	DBAASPS_17341_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0079	Antimicrobial	-	20 µM	Escherichia coli DSM 30083	Not reported by source	DBAASPS_17342_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0080	Antimicrobial	-	20 µM	Bacillus subtilis DSM 402	Not reported by source	DBAASPS_17342_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0081	Antimicrobial	-	20 µM	Escherichia coli DSM 30083	Not reported by source	DBAASPS_17343_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0082	Antimicrobial	-	5 µM	Bacillus subtilis DSM 402	Not reported by source	DBAASPS_17343_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0011	Antimicrobial	-	16 µM	Escherichia coli D31	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0012	Antimicrobial	-	8.0 µM	Staphylococcus aureus ATCC BAA-44	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0013	Antimicrobial	-	5 µg/ml	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0014	Antimicrobial	-	20 µg/ml	Pseudomonas aeruginosa ATCC 27853	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0015	Antimicrobial	-	5 µg/ml	Staphylococcus aureus ATCC 25923	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0016	Antimicrobial	-	29 µM	Escherichia coli D31	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0017	Antimicrobial	-	15 µM	Staphylococcus aureus ATCC BAA-44	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0018	Antimicrobial	-	16 µM	Fusarium solani	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0019	Antimicrobial	-	32 µM	Fusarium oxysporum	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0020	Antimicrobial	-	12.5 µM	Staphylococcus aureus USA 100	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0021	Antimicrobial	-	12.5 µM	Staphylococcus aureus USA 300	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0022	Antimicrobial	-	>100 µM	Pseudomonas aeruginosa ATCC 9027	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0023	Antimicrobial	-	>100 µM	Candida albicans ATCC 90028	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0024	Antimicrobial	-	2 µg/ml	Bacillus subtilis 168	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0025	Antimicrobial	-	16 µg/ml	Staphylococcus aureus DSM 20231	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0026	Antimicrobial	-	16 µg/ml	Staphylococcus aureus SG511	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0027	Antimicrobial	-	8 µg/ml	Staphylococcus aureus ATCC 43300	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0028	Antimicrobial	-	96 µg/ml	Staphylococcus aureus COL	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0029	Antimicrobial	-	64 µg/ml	Staphylococcus aureus MU50	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0030	Antimicrobial	-	32 µg/ml	Escherichia coli DSM 30083	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0031	Antimicrobial	-	>64 µg/ml	Escherichia coli W3110	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0032	Antimicrobial	-	32 µg/ml	Acinetobacter baumannii DSM 30007	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0033	Antimicrobial	-	>64 µg/ml	Pseudomonas aeruginosa PAO1	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0034	Antimicrobial	-	21 µM	Escherichia coli DSM 30083	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0035	Antimicrobial	-	21 µM	Acinetobacter baumannii DSM 30007	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0036	Antimicrobial	-	>100 µM	Pseudomonas aeruginosa DSM 50071	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0037	Antimicrobial	-	1.3 µM	Bacillus subtilis DSM 402	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0038	Antimicrobial	-	11 µM	Staphylococcus aureus DSM 20231	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0039	Antimicrobial	-	5.3 µM	Staphylococcus aureus ATCC 43300	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0040	Antimicrobial	-	2.1±0.7 µM	Staphylococcus aureus 133	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0041	Antimicrobial	-	5.0±0.0 µM	Staphylococcus simulans 22	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0042	Antimicrobial	-	6.7±2.9 µM	Staphylococcus aureus SG511	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0043	Antimicrobial	-	3.5±1.8 µM	Bacillus subtilis DSM 402	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0044	Antimicrobial	-	0.8±0.7 µM	Bacillus megaterium	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0045	Antimicrobial	-	0.6±0.0 µM	Micrococcus luteus	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0046	Antimicrobial	-	143±21 µM	Human hepatocellular carcinoma HepG2	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0047	Antimicrobial	-	132±12 µM	Human colon adenocarcinoma HT29	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0048	Antimicrobial	-	159±7 µM	Human breast adenocarcinoma MCF-7	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0049	Antimicrobial	-	21 µM	Escherichia coli DSM 30083	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0050	Antimicrobial	-	85 µM	Acinetobacter baumannii DSM 30007	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0051	Antimicrobial	-	NA	Pseudomonas aeruginosa DSM 50071	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0052	Antimicrobial	-	11 µM	Staphylococcus aureus DSM 20231	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0053	Antimicrobial	-	6 µM	Staphylococcus aureus ATCC 43300	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0054	Antimicrobial	-	3 µM	Bacillus subtilis DSM 402	Not reported by source	DBAASPS_260_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0055	Antimicrobial	-	23 µM	Escherichia coli DH5alpha	Not reported by source	DBAASPS_6240_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0056	Antimicrobial	-	9 µM	Bacillus subtilis DSM 357	Not reported by source	DBAASPS_6240_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0057	Antimicrobial	-	50 µM	Escherichia coli LWF+	Not reported by source	DBAASPS_6240_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0058	Antimicrobial	-	>100 µM	Bacillus subtilis L170	Not reported by source	DBAASPS_6240_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0059	Antimicrobial	-	21 µM	Escherichia coli DH5alpha	Not reported by source	DBAASPS_6242_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0060	Antimicrobial	-	9 µM	Bacillus subtilis DSM 357	Not reported by source	DBAASPS_6242_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0061	Antimicrobial	-	50 µM	Escherichia coli LWF+	Not reported by source	DBAASPS_6242_chain0dbaasp / linked
CTPDB_P076514_ACT_dbaasp_0062	Antimicrobial	-	>100 µM	Bacillus subtilis L170	Not reported by source	DBAASPS_6242_chain0dbaasp / linked
CTPDB_P076514_ACT_dramp_0083	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	DRAMP03917dramp / linked
CTPDB_P076514_ACT_dramp_0084	Antimicrobial	Antifungal	Not available in the current structured import	Unknown	Not reported by source	DRAMP03917dramp / linked
CTPDB_P076514_ACT_hemolytik_0085	Toxicity	Hemolytic	102.0 µM	Erythrocytes	Not reported by source	1079hemolytik / linked
CTPDB_P076514_ACT_satpdb_0086	Antiviral	-	Not available in the current structured import	Unknown	Not reported by source	satpdb19848satpdb / linked
CTPDB_P076514_ACT_satpdb_0087	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	satpdb19848satpdb / linked
CTPDB_P076514_ACT_satpdb_0088	Toxicity	General Toxic	Not available in the current structured import	Unknown	Not reported by source	satpdb21349satpdb / linked
CTPDB_P076514_ACT_satpdb_0089	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	satpdb21349satpdb / linked

Sequence-linked cross-layer evidence

Linked primary-literature evidence

Records

Papers

Positive

Negative

Primary identities

These observations were collected directly from primary literature and linked by identical normalized sequence. They remain a separate evidence layer and do not overwrite Integrated source-database annotations.

View PEPDIA-PLP-004032 View all experimental records

Provenance

Source database records (20)

Source-specific sequence or modification context. One or more source records use a sequence notation that differs from the canonical backbone. Open each raw sequence before interpreting stereochemistry, terminal groups, or non-standard residues.

apd

AP04276

Raw sequence

RWRWRW

avpdb

AVPdb_AVP1531

Raw sequence

RWRWRW

baamps

EXP00233

Raw sequence

RWRWRW

baamps

EXP00234

Raw sequence

RWRWRW

baamps

EXP00244

Raw sequence

RWRWRW

camp

CAMPSQ11919

Raw sequence

RWRWRW

camp

CAMPSQ13099

Raw sequence

RWRWRW

camp

CAMPSQ17073

Raw sequence

RWRWRW

dbaasp

DBAASPS_260_chain0

Raw sequence

RWRWRW

dbaasp

DBAASPS_6240_chain0

Raw sequence

RWRWRW

dbaasp

DBAASPS_6242_chain0

Raw sequence

rwrwrw

dbaasp

DBAASPS_17339_chain0

Raw sequence

rwrwrw

dbaasp

DBAASPS_17340_chain0

Raw sequence

RWRWRW

dbaasp

DBAASPS_17341_chain0

Raw sequence

rwrwrw

dbaasp

DBAASPS_17342_chain0

Raw sequence

RWRWRW

dbaasp

DBAASPS_17343_chain0

Raw sequence

rwrwrw

dramp

DRAMP03917

Raw sequence

RWRWRW

hemolytik

1079

Raw sequence

RWRWRW

satpdb

satpdb19848

Raw sequence

RWRWRW

satpdb

satpdb21349

Raw sequence

RWRWRW

Citation trail

Literature (12 records)

Modulating the activity of short arginine-tryptophan containing antibacterial peptides with N-terminal metallocenoyl groups.

Albada HB, Chiriac AI, Wenzel M, Penkova M, Bandow JE, Sahl HG, Metzler-Nolte N. 2012

Beilstein J Org Chem2012PMID 23209509

Antiviral activity of selected antimicrobial peptides against vaccinia virus.

Mohan KV, Rao SS, Atreya CD.

Antiviral Res2010PMID 20347875

[{"title": "[Effects of Trp- and Arg-Containing Antimicrobial-Peptide Structure on Inhibition of Escherichia coli Planktonic Growth and Biofilm Formation](https://www.doi.org/10.1128/AEM.02321-09)", "authors": "S. Hou, Z. Liu, A. W. Young, S. L. Mark, N. R. Kallenbach, D. Ren", "publication": "2010.Applied and Environmental Microbiology 6:1967-1974"}]

[{"title": "[Effects of Trp- and Arg-Containing Antimicrobial-Peptide Structure on Inhibition of Escherichia coli Planktonic Growth and Biofilm Formation](https://www.doi.org/10.1128/AEM.02321-09)", "authors": "S. Hou, Z. Liu, A. W. Young, S. L. Mark, N. R. Kallenbach, D. Ren", "publication": "2010.Applied and Environmental Microbiology 6:1967-1974"}]

[{"title": "[Control of Bacterial Persister Cells by Trp/Arg-Containing Antimicrobial Peptides](https://www.doi.org/10.1128/AEM.02440-10)", "authors": "X. Chen, M. Zhang, C. Zhou, N. R. Kallenbach, D. Ren", "publication": "2011.Applied and Environmental Microbiology 14:4878-4885"}]

[{"title": "[Control of Bacterial Persister Cells by Trp/Arg-Containing Antimicrobial Peptides](https://www.doi.org/10.1128/AEM.02440-10)", "authors": "X. Chen, M. Zhang, C. Zhou, N. R. Kallenbach, D. Ren", "publication": "2011.Applied and Environmental Microbiology 14:4878-4885"}]

Length effects in antimicrobial peptides of the (RW)n series

Liu Z, Brady A, Young A, Rasimick B, Chen K, Zhou C, Kallenbach NR

Antimicrob Agents Chemother2007PMID 17145799

Length effects in antimicrobial peptides of the (RW)n series

Liu Z, Brady A, Young A, Rasimick B, Chen K, Zhou C, Kallenbach NR

Antimicrob Agents Chemother2007PMID 23203110

Length effects in antimicrobial peptides of the (RW)n series

Liu Z, Brady A, Young A, Rasimick B, Chen K, Zhou C, Kallenbach NR

Antimicrob Agents Chemother2007PMID 27617260

Length effects in antimicrobial peptides of the (RW)n series

Liu Z, Brady A, Young A, Rasimick B, Chen K, Zhou C, Kallenbach NR

Antimicrob Agents Chemother2007PMID 24900420

Cyclic antimicrobial R-, W-rich peptides: the role of peptide structure and E. coli outer and inner membranes in activity and the mode of action.

Junkes C, Harvey RD, Bruce KD, Dölling R, Bagheri M, Dathe M

Eur Biophys J2011PMID 21286704

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:12.728292+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET

{
  "toxicity": [
    {
      "unit": "µM",
      "value": "210",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Sheep erythrocytes"
    },
    {
      "source_db": "dbaasp",
      "assay_method": "-",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "333",
      "source_db": "dbaasp",
      "assay_method": "17% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "250",
      "source_db": "dbaasp",
      "assay_method": "<10% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "100",
      "source_db": "dbaasp",
      "assay_method": "2% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "100",
      "source_db": "dbaasp",
      "assay_method": "2% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "333",
      "source_db": "dbaasp",
      "assay_method": "0% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    }
  ]
}

Source metadata

[
  {
    "source_db": "apd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "avpdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "baamps",
    "organism_name": "Unknown"
  },
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "hemolytik",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CCCCCC"
}