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PEPDIA-INT-081761

Gold

Mastoparan-L

85

Quality

7

Source DBs

126

Activities

28

Source refs

20

Literature

1

Patents

Integrated record

Sequence and molecular profile

INLKALAALAKKIL
Indexed sequence14 aa
1INLKALAALAKKIL

Length

14

Molecular weight

1479.92 Da

Formula

C70H130N18O16

Structure type

Linear

Synthesis

Ribosomal

Chirality

L

Family

-

Gene

-

Residue composition

L
4
A
4
K
3
I
2
N
1

Physicochemical profile

Hydrophobic10

Membrane affinity proxy

Polar1

Solubility proxy

Charged3

Net charge proxy +3

Aromatic0

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

1479.892 Da

Molecular formula

C70H130N18O16

Theoretical pI

10.3021

Net charge at pH 7

2.7571

GRAVY

1.1571

Instability index

10.9143

Aromaticity

0

Topological polar surface area

562.77 Ų

cLogP

-1.6807

Hydrogen-bond donors

19

Hydrogen-bond acceptors

19

Rotatable bonds

53

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

INLKALAALAKKIL

HELM 2.0

validated simple linear

PEPTIDE1{I.N.L.K.A.L.A.A.L.A.K.K.I.L}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(N)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(C(=O)NC(CC(C)C)C(=O)O)C(C)CC

Isomeric SMILES

validated

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](C)CC

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-081761,
  title = {Mastoparan-L},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-081761},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Mastoparan-L. (2026). PepDiana record PEPDIA-INT-081761. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-081761

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (126 records)

Stable recordActivitySubtypeValueTargetAssay methodSource
CTPDB_P081761_ACT_apd_0000AntimicrobialAnti-Gram+Not available in the current structured importUnknownNot reported by sourceAP00201apd / linked
CTPDB_P081761_ACT_apd_0002Anticancer-Not available in the current structured importUnknownNot reported by sourceAP00201apd / linked
CTPDB_P081761_ACT_camp_0005AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceCAMPSQ8238camp / linked
CTPDB_P081761_ACT_camp_0006AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceCAMPSQ8239camp / linked
CTPDB_P081761_ACT_camp_0007AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceCAMPSQ8242camp / linked
CTPDB_P081761_ACT_camp_0008AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceCAMPSQ8243camp / linked
CTPDB_P081761_ACT_camp_0003AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceCAMPSQ9945camp / linked
CTPDB_P081761_ACT_camp_0004AntimicrobialAnti-Gram-Not available in the current structured importUnknownNot reported by sourceCAMPSQ9945camp / linked
CTPDB_P081761_ACT_cppsite_0009Cell-PenetratingCPPNot available in the current structured importUnknownNot reported by source1060cppsite / linked
CTPDB_P081761_ACT_cppsite_0010Cell-PenetratingCPPNot available in the current structured importUnknownNot reported by source2640cppsite / linked
CTPDB_P081761_ACT_cppsite_0011Cell-PenetratingCPPNot available in the current structured importUnknownNot reported by source2641cppsite / linked
CTPDB_P081761_ACT_cppsite_0012Cell-PenetratingCPPNot available in the current structured importUnknownNot reported by source2836cppsite / linked
CTPDB_P081761_ACT_dbaasp_0084Antimicrobial-45.92 µMHuman astrocytoma U373-MGNot reported by sourceDBAASPS_12888_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0085Antimicrobial-13.31 µMRat leukemia cells RBL-2H3Not reported by sourceDBAASPS_12888_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0086Antimicrobial-2.7 µMAcinetobacter baumannii CR17Not reported by sourceDBAASPS_12888_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0087Antimicrobial-10 µMHuman cervical carcinoma HeLaNot reported by sourceDBAASPS_12888_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0088Antimicrobial-10.5 µMAcinetobacter baumannii CR17Not reported by sourceDBAASPS_15027_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0089Antimicrobial-21 µMAcinetobacter baumannii CR86Not reported by sourceDBAASPS_15027_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0090Antimicrobial-42 µMAcinetobacter baumannii Ab11Not reported by sourceDBAASPS_15027_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0091Antimicrobial-2.6 µMAcinetobacter baumannii CR17Not reported by sourceDBAASPS_15028_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0092Antimicrobial-2.6 µMAcinetobacter baumannii CR86Not reported by sourceDBAASPS_15028_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0093Antimicrobial-2.6 µMAcinetobacter baumannii Ab11Not reported by sourceDBAASPS_15028_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0094Antimicrobial-13 µMHuman cervical carcinoma HeLaNot reported by sourceDBAASPS_15028_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0095Antimicrobial-21.6 µMAcinetobacter baumannii CR17Not reported by sourceDBAASPS_15030_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0096Antimicrobial-21.6 µMAcinetobacter baumannii CR86Not reported by sourceDBAASPS_15030_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0097Antimicrobial-43.3 µMAcinetobacter baumannii Ab11Not reported by sourceDBAASPS_15030_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0098Antimicrobial-43.3 µMAcinetobacter baumannii Ab113Not reported by sourceDBAASPS_15030_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0099Antimicrobial-21.6 µMAcinetobacter baumannii CR17Not reported by sourceDBAASPS_15031_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0100Antimicrobial-43.3 µMAcinetobacter baumannii CR86Not reported by sourceDBAASPS_15031_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0101Antimicrobial-86.5 µMAcinetobacter baumannii Ab11Not reported by sourceDBAASPS_15031_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0102Antimicrobial-173 µMAcinetobacter baumannii Ab113Not reported by sourceDBAASPS_15031_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0013Antimicrobial-6.25 µg/mlEnterococcus faecalis LS-101Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0014Antimicrobial-6.25 µg/mlStaphylococcus aureus 209PNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0015Antimicrobial->25 µg/mlStaphylococcus aureus 1840Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0016Antimicrobial-6.25 µg/mlStaphylococcus epidermidis ATCC 12228Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0017Antimicrobial-3.13 µg/mlBacillus subtilis PCI 219Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0018Antimicrobial->25 µg/mlEscherichia coli NIHJ JC-2Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0019Antimicrobial->25 µg/mlShigella flexneri EW-10Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0020Antimicrobial-25 µg/mlShigella sonnei EW-33Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0021Antimicrobial->25 µg/mlKlebsiella pneumoniaeNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0022Antimicrobial-50 µMEscherichia coli ATCC 11775Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0023Antimicrobial-5 µMStaphylococcus aureus ATCC 12600Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0024Antimicrobial-25 µMCandida albicans ATCC 10231Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0025Antimicrobial-8 µMBotrytis cinereaNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0026Antimicrobial-34 µMLymantria dispar FB cellsNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0027Antimicrobial-50 µMSpodoptera frugiperda ovarian Sf9 cellsNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0028Antimicrobial-25 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0029Antimicrobial->50 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0030Antimicrobial-12.5 µMEscherichia coli DH5alphaNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0031Antimicrobial->50 µMEscherichia coli DH5alphaNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0032Antimicrobial->50 µMSerratia marcescens ATCC 133880Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0033Antimicrobial-50 µMPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0034Antimicrobial-12.5 µMKlebsiella pneumoniae ATCC 13833Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0035Antimicrobial-25 µMKlebsiella pneumoniae ATCC 13833Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0036Antimicrobial-50 µMSalmonella enterica subsp. enterica serovar Typhimurium ATCC 13311Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0037Antimicrobial-50 µMHaemophilus influenzae ATCC 19418Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0038Antimicrobial-6.3 µMBacillus subtilis ATCC 6051Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0039Antimicrobial-12.5 µMBacillus subtilis ATCC 6051Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0040Antimicrobial-25 µMListeria monocytogenes NCTC 11994Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0041Antimicrobial-6.3 µMMicrococcus luteus ATCC 9341Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0042Antimicrobial-25 µMEnterococcus faecalis ATCC 19433Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0043Antimicrobial-12.5 µMStaphylococcus aureus ATCC 292136.3Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0044Antimicrobial-25 µMStaphylococcus aureus ATCC 292136.3Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0045Antimicrobial-12.5 µMStreptococcus pneumoniae ATCC 33400Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0046Antimicrobial-25 µMNocardia asteroides ATCC 3308Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0047Antimicrobial-3.1 µMNeurospora crassa FGSC 2489Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0048Antimicrobial-3.1 µMBotrytis cinerea MUCL 30158Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0049Antimicrobial-1.6 µMFusarium culmorum MUCL 30162Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0050Antimicrobial-5 µMSaccharomyces cerevisiae W303-1ANot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0051Antimicrobial->44.3 µg/mlMalassezia sympodialis ATCC 42132Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0052Antimicrobial-2.7 µMAcinetobacter baumannii CR17Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0053Antimicrobial-32 µMHuman cervical carcinoma HeLaNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0054Antimicrobial-600 µg/mlMycobacterium tuberculosis H37RvNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0055Antimicrobial-150 µg/mlMycobacterium tuberculosisNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0056Antimicrobial-1200 µg/mlMycobacterium tuberculosis 85Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0057Antimicrobial-32-64 µg/mlMycobacterium tuberculosisNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0058Antimicrobial->128 µg/mlMycobacterium aviumNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0059Antimicrobial-28.67 µMHuman astrocytoma U373-MGNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0060Antimicrobial-21.54 µMRat leukemia cells RBL-2H3Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0061Antimicrobial->32 µMAcinetobacter baumanniiNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0062Antimicrobial->32 µMEnterobacter cloacaeNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0063Antimicrobial-32 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0064Antimicrobial->32 µMEscherichia coli KpC+001812446Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0065Antimicrobial-2 µMEscherichia coli BL21Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0066Antimicrobial->32 µMKlebsiella pneumoniae ATCC 13883Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0067Antimicrobial->32 µMKlebsiella pneumoniae KpC+001825971Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0068Antimicrobial->32 µMStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0069Antimicrobial-8 µMStaphylococcus aureus ATCC 12600Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0070Antimicrobial->32 µMStaphylococcus aureus MRNot reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0071Antimicrobial-8 µMPseudomonas aeruginosa PA14Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0072Antimicrobial-8 µMPseudomonas aeruginosa PAO1Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0073Antimicrobial-12.5 µMHuman prostate adenocarcinoma PC-3Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0074Antimicrobial-25 µMHuman breast adenocarcinoma MCF-7Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0075Antimicrobial-25 µMHuman colon adenocarcinoma HT29Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0076Antimicrobial-64 µMListeria monocytogenes ATCC 15313Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0077Antimicrobial-128 µMStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0078Antimicrobial->128 µMBacillus cereus ATCC 11778Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0079Antimicrobial-128 µMEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0080Antimicrobial-8 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0081Antimicrobial-16 µMSalmonella enterica subsp. enterica serovar Enteritidis ATCC 13076Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0082Antimicrobial-128 µMPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dbaasp_0083Antimicrobial-32 µMCandida albicans ATCC 10231Not reported by sourceDBAASPS_3343_chain0dbaasp / linked
CTPDB_P081761_ACT_dramp_0112Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP05649dramp / linked
CTPDB_P081761_ACT_dramp_0103Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP18665dramp / linked
CTPDB_P081761_ACT_dramp_0104AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceDRAMP18665dramp / linked
CTPDB_P081761_ACT_dramp_0105AntimicrobialAnti-Gram+Not available in the current structured importUnknownNot reported by sourceDRAMP18665dramp / linked
CTPDB_P081761_ACT_dramp_0106AntimicrobialAnti-Gram-Not available in the current structured importUnknownNot reported by sourceDRAMP18665dramp / linked
CTPDB_P081761_ACT_dramp_0107Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP18709dramp / linked
CTPDB_P081761_ACT_dramp_0108AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceDRAMP18709dramp / linked
CTPDB_P081761_ACT_dramp_0109UnknownCell degranulatingNot available in the current structured importUnknownNot reported by sourceDRAMP18709dramp / linked
CTPDB_P081761_ACT_dramp_0110Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP33555dramp / linked
CTPDB_P081761_ACT_dramp_0111Anticancer-Not available in the current structured importUnknownNot reported by sourceDRAMP33555dramp / linked
CTPDB_P081761_ACT_hemolytik_0116ToxicityHemolytic50.0 µMErythrocytesNot reported by source1282hemolytik / linked
CTPDB_P081761_ACT_hemolytik_0117ToxicityHemolytic50.0 mMErythrocytesNot reported by source1732hemolytik / linked
CTPDB_P081761_ACT_hemolytik_0113ToxicityHemolytic100.0 µMErythrocytesNot reported by source2013hemolytik / linked
CTPDB_P081761_ACT_hemolytik_0114ToxicityHemolytic50.0 µMErythrocytesNot reported by source2014hemolytik / linked
CTPDB_P081761_ACT_hemolytik_0115ToxicityHemolytic100.0 µMErythrocytesNot reported by source3753hemolytik / linked
CTPDB_P081761_ACT_satpdb_0118AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourcesatpdb12506satpdb / linked
CTPDB_P081761_ACT_satpdb_0119ToxicityGeneral ToxicNot available in the current structured importUnknownNot reported by sourcesatpdb12506satpdb / linked
CTPDB_P081761_ACT_satpdb_0120Antimicrobial-Not available in the current structured importUnknownNot reported by sourcesatpdb12506satpdb / linked
CTPDB_P081761_ACT_satpdb_0121AntimicrobialAntifungalNot available in the current structured importUnknownNot reported by sourcesatpdb12506satpdb / linked
CTPDB_P081761_ACT_satpdb_0122Cell-PenetratingDrug DeliveryNot available in the current structured importUnknownNot reported by sourcesatpdb17103satpdb / linked
CTPDB_P081761_ACT_satpdb_0123Anticancer-Not available in the current structured importUnknownNot reported by sourcesatpdb18344satpdb / linked
CTPDB_P081761_ACT_satpdb_0124AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourcesatpdb18344satpdb / linked
CTPDB_P081761_ACT_satpdb_0125ToxicityGeneral ToxicNot available in the current structured importUnknownNot reported by sourcesatpdb18344satpdb / linked
CTPDB_P081761_ACT_satpdb_0126Antimicrobial-Not available in the current structured importUnknownNot reported by sourcesatpdb18344satpdb / linked

Sequence-linked cross-layer evidence

Linked primary-literature evidence

4

Records

2

Papers

4

Positive

0

Negative

1

Primary identities

These observations were collected directly from primary literature and linked by identical normalized sequence. They remain a separate evidence layer and do not overwrite Integrated source-database annotations.

View PEPDIA-PLP-003679View all experimental records

Provenance

Source database records (28)

Source-specific sequence or modification context. One or more source records use a sequence notation that differs from the canonical backbone. Open each raw sequence before interpreting stereochemistry, terminal groups, or non-standard residues.

apd

AP00201

Raw sequence

INLKALAALAKKIL

camp

CAMPSQ9945

Raw sequence

INLKALAALAKKIL

camp

CAMPSQ8238

Raw sequence

iNLKALAALAKKIL

camp

CAMPSQ8239

Raw sequence

InLKALAALAKKIL

camp

CAMPSQ8242

Raw sequence

inlkalaalakkil

camp

CAMPSQ8243

Raw sequence

INLKALAALAKKIL

cppsite

1060

Raw sequence

INLKALAALAKKIL

cppsite

2640

Raw sequence

INLKALAALAKKIL

cppsite

2641

Raw sequence

inlkalaalakkil

cppsite

2836

Raw sequence

inlkalaalakkil

dbaasp

DBAASPS_3343_chain0

Raw sequence

INLKALAALAKKIL

dbaasp

DBAASPS_12888_chain0

Raw sequence

inlkalaalakkil

dbaasp

DBAASPS_15027_chain0

Raw sequence

INLKALAALAKKIL

dbaasp

DBAASPS_15028_chain0

Raw sequence

INLKALAALAKKIL

dbaasp

DBAASPS_15030_chain0

Raw sequence

iNLKALAALAKKIL

dbaasp

DBAASPS_15031_chain0

Raw sequence

InLKALAALAKKIL

dramp

DRAMP18665

Raw sequence

INLKALAALAKKIL

dramp

DRAMP18709

Raw sequence

INLKALAALAKKIL

dramp

DRAMP33555

Raw sequence

inlkalaalakkil

dramp

DRAMP05649

Raw sequence

INLKALAALAKKIL

hemolytik

2013

Raw sequence

INLKALAALAKKIL

hemolytik

2014

Raw sequence

INLKALAALAKKIL

hemolytik

3753

Raw sequence

INLKALAALAKKIL

hemolytik

1282

Raw sequence

INLKALAALAKKIL

hemolytik

1732

Raw sequence

INLKALAALAKKIL

satpdb

satpdb12506

Raw sequence

INLKALAALAKKIL

satpdb

satpdb17103

Raw sequence

INLKALAALAKKIL

satpdb

satpdb18344

Raw sequence

INLKALAALAKKIL

Citation trail

Literature (20 records)

{"reference": "Chem Pharm Bull (Tokyo). 1979 Aug;27(8):1942-4", "title": "A new mast cell degranulating peptide \"mastoparan\" in the venom of Vespula lewisii", "author": "García JR, Krause A, Schulz S, Rodríguez-Jiménez FJ, Klüver E, Adermann K, Forssmann U, Frimpong-Boateng A, Bals R, Forssmann WG1979"}

{"reference": "Chem Pharm Bull (Tokyo). 1979 Aug;27(8):1942-4", "title": "A new mast cell degranulating peptide \"mastoparan\" in the venom of Vespula lewisii", "author": "García JR, Krause A, Schulz S, Rodríguez-Jiménez FJ, Klüver E, Adermann K, Forssmann U, Frimpong-Boateng A, Bals R, Forssmann WG1979"}

--

Interaction of mastoparan-B from venom of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity.

Park NG, Yamato Y, Lee S, Sugihara G

Biopolymers1995PMID 8555423

Interaction of mastoparan-B from venom of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity.

Park NG, Yamato Y, Lee S, Sugihara G

Biopolymers1995PMID 21184791

Interaction of mastoparan-B from venom of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity.

Park NG, Yamato Y, Lee S, Sugihara G

Biopolymers1995PMID 12354111

Interaction of mastoparan-B from venom of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity.

Park NG, Yamato Y, Lee S, Sugihara G

Biopolymers1995PMID 22023266

Interaction of mastoparan-B from venom of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity.

Park NG, Yamato Y, Lee S, Sugihara G

Biopolymers1995PMID 22569076

Interaction of mastoparan-B from venom of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity.

Park NG, Yamato Y, Lee S, Sugihara G

Biopolymers1995PMID 30570475

Interaction of mastoparan-B from venom of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity.

Park NG, Yamato Y, Lee S, Sugihara G

Biopolymers1995PMID 39617871

Selective amino acid substitution reduces cytotoxicity of the antimicrobial peptide mastoparan.

Irazazabal LN, Porto WF, Ribeiro SM, Casale S, Humblot V, Ladram A, Franco OL.

Biochim Biophys Acta2016PMID 27423268

A new mast cell degranulating peptide mastoparan in the venom of Vespula lewisii

Hirai Y, Yasuhara T, Yoshida H, Nakajima T, Fujino M, Kitada C.

Chem Pharm Bull (Tokyo)1979PMID 540362

IP evidence

Patents (1)

US 20050260715

dramp

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:11.941613+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET
{
  "toxicity": [
    {
      "unit": "µM",
      "value": "100",
      "source_db": "dbaasp",
      "assay_method": "10% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "12.5",
      "source_db": "dbaasp",
      "assay_method": "50% Cell death",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Mouse fibroblasts 3T3-L1"
    },
    {
      "unit": "µM",
      "value": "50",
      "source_db": "dbaasp",
      "assay_method": "50% Cell death",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human umbilical vein endothelial cells HUVEC"
    },
    {
      "unit": "µM",
      "value": "100",
      "source_db": "dbaasp",
      "assay_method": "45% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "8",
      "source_db": "dbaasp",
      "assay_method": "<5% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "128",
      "source_db": "dbaasp",
      "assay_method": "28% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "source_db": "dramp",
      "assay_method": "[Ref.27423268]40% hemolysis at 10μM against rat red blood cells",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Erythrocytes"
    }
  ]
}
Source metadata
[
  {
    "source_db": "apd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "cppsite",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "hemolytik",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]
Structure metadata
{
  "pdb_id": [
    "1D7N resolved by NMR.",
    "1D7N resolved by NMR"
  ],
  "source_db": "dramp"
}