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PEPDIA-INT-064041

Gold

Unnamed peptide

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

YPFPGPI

Indexed sequence7 aa

1YPFPGPI

Length

Molecular weight

789.93 Da

Formula

C41H55N7O9

Structure type

Linear

Synthesis

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic3

Membrane affinity proxy

Polar0

Solubility proxy

Charged0

Net charge proxy +0

Aromatic2

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

789.9168 Da

Molecular formula

C41H55N7O9

Theoretical pI

5.5243

Net charge at pH 7

-0.2409

GRAVY

0.1143

Instability index

81.2286

Aromaticity

0.2857

Topological polar surface area

231.78 Å²

cLogP

0.6942

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

YPFPGPI

HELM 2.0

validated simple linear

PEPTIDE1{Y.P.F.P.G.P.I}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(NC(=O)C1CCCN1C(=O)CNC(=O)C1CCCN1C(=O)C(Cc1ccccc1)NC(=O)C1CCCN1C(=O)C(N)Cc1ccc(O)cc1)C(=O)O

Isomeric SMILES

validated

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-064041,
  title = {Unnamed peptide},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-064041},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Unnamed peptide. (2026). PepDiana record PEPDIA-INT-064041. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-064041

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (13 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P064041_ACT_ahtpdb_0001	Metabolic/Cardiovascular	ACE Inhibitor	299.25 µM	Unknown	Not reported by source	2476ahtpdb / linked
CTPDB_P064041_ACT_ahtpdb_0002	Metabolic/Cardiovascular	ACE Inhibitor	Not available for this observation	Unknown	Not reported by source	3430ahtpdb / linked
CTPDB_P064041_ACT_ahtpdb_0003	Metabolic/Cardiovascular	ACE Inhibitor	Not available for this observation	Unknown	Not reported by source	3461ahtpdb / linked
CTPDB_P064041_ACT_ahtpdb_0000	Metabolic/Cardiovascular	ACE Inhibitor	Not available for this observation	Unknown	Not reported by source	4268ahtpdb / linked
CTPDB_P064041_ACT_ahtpdb_0004	Metabolic/Cardiovascular	ACE Inhibitor	500.0 µM	Unknown	Not reported by source	6651ahtpdb / linked
CTPDB_P064041_ACT_fermfoodb_0005	Neuroactive/Ion Channel	Analgesic	Not available in the current structured import	Unknown	LC-MS with Q Exactive Plus hybridquadrupole-Orbitrap mass spectrometer	FermFooDB_Casein_FMDB1751fermfoodb / linked
CTPDB_P064041_ACT_fermfoodb_0006	Neuroactive/Ion Channel	Analgesic	Not available in the current structured import	Unknown	LC-MS with Q Exactive Plus hybridquadrupole-Orbitrap mass spectrometer	FermFooDB_Casein_FMDB1752fermfoodb / linked
CTPDB_P064041_ACT_fermfoodb_0007	Neuroactive/Ion Channel	Analgesic	Not available in the current structured import	Unknown	LC-MS with Q Exactive Plus hybridquadrupole-Orbitrap mass spectrometer	FermFooDB_Casein_FMDB1753fermfoodb / linked
CTPDB_P064041_ACT_fermfoodb_0008	Neuroactive/Ion Channel	Analgesic	Not available in the current structured import	Unknown	LC-MS with Q Exactive Plus hybridquadrupole-Orbitrap mass spectrometer	FermFooDB_Casein_FMDB1754fermfoodb / linked
CTPDB_P064041_ACT_fermfoodb_0011	Neuroactive/Ion Channel	Analgesic	Not available in the current structured import	Unknown	LC-MS with Q Exactive Plus hybridquadrupole-Orbitrap mass spectrometer	FermFooDB_milk_FMDB1751fermfoodb / linked
CTPDB_P064041_ACT_fermfoodb_0010	Neuroactive/Ion Channel	Analgesic	Not available in the current structured import	Unknown	LC-MS with Q Exactive Plus hybridquadrupole-Orbitrap mass spectrometer	FermFooDB_milk_FMDB1752fermfoodb / linked
CTPDB_P064041_ACT_fermfoodb_0009	Neuroactive/Ion Channel	Analgesic	Not available in the current structured import	Unknown	LC-MS with Q Exactive Plus hybridquadrupole-Orbitrap mass spectrometer	FermFooDB_milk_FMDB1753fermfoodb / linked
CTPDB_P064041_ACT_satpdb_0012	Metabolic/Cardiovascular	Antihypertensive	Not available for this observation	Unknown	Not reported by source	satpdb27350satpdb / linked

Sequence-linked cross-layer evidence

Linked primary-literature evidence

Records

Papers

Positive

Negative

Primary identities

These observations were collected directly from primary literature and linked by identical normalized sequence. They remain a separate evidence layer and do not overwrite Integrated source-database annotations.

View PEPDIA-PLP-004198 View all experimental records

Provenance

Source database records (13)

ahtpdb

4268

Raw sequence

YPFPGPI

ahtpdb

2476

Raw sequence

YPFPGPI

ahtpdb

6651

Raw sequence

YPFPGPI

ahtpdb

3430

Raw sequence

YPFPGPI

ahtpdb

3461

Raw sequence

YPFPGPI

fermfoodb

FermFooDB_Casein_FMDB1751

Raw sequence

YPFPGPI

fermfoodb

FermFooDB_Casein_FMDB1752

Raw sequence

YPFPGPI

fermfoodb

FermFooDB_Casein_FMDB1753

Raw sequence

YPFPGPI

fermfoodb

FermFooDB_Casein_FMDB1754

Raw sequence

YPFPGPI

fermfoodb

FermFooDB_milk_FMDB1753

Raw sequence

YPFPGPI

fermfoodb

FermFooDB_milk_FMDB1752

Raw sequence

YPFPGPI

fermfoodb

FermFooDB_milk_FMDB1751

Raw sequence

YPFPGPI

satpdb

satpdb27350

Raw sequence

YPFPGPI

Citation trail

Literature (6 records)

Bioactive peptides derived from milk proteins and their health beneficial potentials: an update.

Nagpal R1, Behare P, Rana R, Kumar A, Kumar M, Arora S, Morotta F, Jain S, Yadav H.

Food Funct. 2011 Jan;2(1):18-27.2011PMID 21773582

A new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides.

Sagardia I1, Roa-Ureta RH, Bald C.

Food Chem. 2013 Feb 15;136(3-4):1370-6.2013PMID 23194537

ACE inhibitory peptides

Yoshinori Mine, Fereidoon Shahidi

Nutraceutical Proteins and Peptides in Health and Disease (Nutraceutical Science and Technology)2005

Animal and Plant Proteins as Precursors of Peptides with ACE Inhibitory Activity – An in silico Strategy of Protein Evaluation

Anna Iwaniak and Jerzy Dziuba

Food Technol. Biotechnol. 47 (4) 441–449 (2009)2009

-

--PMID 26616950

-

--PMID 12058981

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:10.991164+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata

[
  {
    "source_db": "ahtpdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "fermfoodb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CCCCSCC"
}