ProForma 2.0
Not calculated for this record
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Primary-literature peptidemedium evidence PepDiana evidence grade for a literature-derived identity; Medium indicates retained review flags, while High has no unresolved review flag.
PEPDIA-PLP-004198
pep_013
Aliases: pep_013, β-casomorphin-7 (β-CM7)
Normalized sequence
YPFPGPI
7 amino acids
Release PepDiana-V1-20260620
5
Activity records
2
Source papers
5
Positive
0
Negative / threshold
Cross-layer links
Related Integrated records
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.
Computed properties
physchem-20260620Molecular weight
Not calculated
Molecular formula
Not calculated
Theoretical pI
Not calculated
Net charge at pH 7
Not calculated
GRAVY
Not calculated
Instability index
Not calculated
Aromaticity
Not calculated
Topological polar surface area
Not calculated
cLogP
Not calculated
Hydrogen-bond donors
Not calculated
Hydrogen-bond acceptors
Not calculated
Rotatable bonds
Not calculated
Method: Not recorded
Tool: Not recorded
Calculated: Not recorded
Sequence representations
HELM 2.0
Not calculated for this record
Canonical SMILES
Not calculated for this record
Isomeric SMILES
Not calculated for this record
Paper-level observations
Experimental evidence grouped by activity
Other 2 records
PMC13003480
2 observationsOtherPositive observation
Record detail In the present study, fragment YPFPGPI (Y60–I66), corresponding to the β-casomorphin-7 (β-CM7) peptide, was also identified after gastrointestinal digestion of both yogurts. ... this peptide was detected with ... in the A1/A2 yogurt digest (8.26 × 10^6 AUC).
- Measure
- other
- Value
- 8.26 × 10^6 AUC
- Target
- Not reported by source
- Assay
- Not reported by source
OtherPositive observation
Record detail In the present study, fragment YPFPGPI (Y60–I66), corresponding to the β-casomorphin-7 (β-CM7) peptide, was also identified after gastrointestinal digestion of both yogurts. ... this peptide was detected with greater intensity in the A2/A2 yogurt digest (1.57 × 10^7 AUC) compared to the A1/A2 yogurt digest (8.26 × 10^6 AUC).
- Measure
- other
- Value
- 1.57 × 10^7 AUC
- Target
- Not reported by source
- Assay
- Not reported by source
Antioxidant 2 records
PMC7466261
2 observationsAntioxidantORACPositive observation
Record detail Table 4: YPFPGPI ORAC 1.91 ± 0.14 µmol TE/µmol peptide.
- Measure
- other
- Value
- 1.91 other (ORAC)
- Target
- Not reported by source
- Assay
- Not reported by source
AntioxidantABTSPositive observation
Record detail Table 4: YPFPGPI TEAC 1.62 ± 0.08 µmol TE/µmol peptide.
- Measure
- other
- Value
- 1.62 other (TEAC)
- Target
- Not reported by source
- Assay
- Not reported by source
Metabolic/Cardiovascular 1 records
PMC7466261
1 observationsMetabolic/CardiovascularACE InhibitorPositive observation
Record detail Table 4: YPFPGPI ACE IC50 685.91 ± 102.91 µM.
- Measure
- other
- Value
- 685.91 µM
- Target
- Angiotensin-converting enzyme
- Assay
- Not reported by source
Citation and release provenance
Cite this identity as PepDiana record PEPDIA-PLP-004198, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.
Record updated: 2026-06-22T07:14:26.229247+00:00