ProForma 2.0
not generated modification context
Not calculated for this record
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PEPDIA-INT-008079
GoldPepDiana tier derived from the internal quality score plus activity and literature coverage; it is not an external database rating.Sequence 35 from Patent US 10351599
75
Quality PepDiana 0–100 composite of sequence, source, activity, literature, and cross-database evidence completeness.
5
Source DBs
16
Activities
22
Source refs
6
Literature
2
Patents
Integrated record
Sequence and molecular profile
CYFQNCPRG
Indexed sequence9 aa
1CYFQNCPRG
Length
9
Molecular weight
-
Formula
-
Structure type
Cyclic
Synthesis
-
Chirality
L
Family
-
Gene
-
Residue composition
C
2
Y
1
F
1
Q
1
N
1
P
1
R
1
G
1
Physicochemical profile
Hydrophobic2
Membrane affinity proxy
Polar4
Solubility proxy
Charged1
Net charge proxy +1
Aromatic2
Binding interaction proxy
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.
Computed properties
physchem-20260620Molecular weight
1087.2321 Da
Molecular formula
Not calculated
Theoretical pI
8.0582
Net charge at pH 7
0.7393
GRAVY
-0.7778
Instability index
9.2778
Aromaticity
0.2222
Topological polar surface area
Not calculated
cLogP
Not calculated
Hydrogen-bond donors
Not calculated
Hydrogen-bond acceptors
Not calculated
Rotatable bonds
Not calculated
Method: PepDiana sequence/structure descriptor pipeline
Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6
Calculated: 2026-06-20T11:01:38.358971+00:00
Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200
Sequence representations
HELM 2.0
not generated modification context
Not calculated for this record
Canonical SMILES
not generated modification context
Not calculated for this record
Isomeric SMILES
not generated modification context
Not calculated for this record
Follow-up research
External analysis tools
Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.
Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.
Research workflow
Citation and local history
BibTeX
@misc{PEPDIA-INT-008079,
title = {Sequence 35 from Patent US 10351599},
author = {{PepDiana Consortium}},
year = {2026},
howpublished = {PepDiana Multifunctional Peptide Database},
url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-008079},
note = {Accessed from local PepDiana development build}
}APA-style note
Sequence 35 from Patent US 10351599. (2026). PepDiana record PEPDIA-INT-008079. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-008079
This record is saved to local recent-view history so it can reappear on the peptide browser page.
Integrated source-database annotations
Biological activity (16 records)
| Stable record | Activity | Subtype | Value | Target | Assay method | Source |
|---|---|---|---|---|---|---|
| CTPDB_P008079_ACT_dramp_0000 | Antimicrobial | - | Not available in the current structured import | Unknown | Not reported by source | DRAMP28578dramp / linked |
| CTPDB_P008079_ACT_dramp_0001 | Antimicrobial | - | Not available in the current structured import | Unknown | Not reported by source | DRAMP28581dramp / linked |
| CTPDB_P008079_ACT_dramp_0002 | Antimicrobial | Antibacterial | Not available in the current structured import | Unknown | Not reported by source | DRAMP28581dramp / linked |
| CTPDB_P008079_ACT_satpdb_0003 | Cell-Penetrating | Drug Delivery | Not available in the current structured import | Unknown | Not reported by source | satpdb13981satpdb / linked |
| CTPDB_P008079_ACT_satpdb_0004 | Bioregulatory | Cell-Cell Communication | Not available in the current structured import | Unknown | Not reported by source | satpdb21220satpdb / linked |
| CTPDB_P008079_ACT_thpdb_0005 | Clinical / Approved Drug | General Therapeutic | Not available in the current structured import | Unknown | Not reported by source | Th1056_10375_rec0thpdb / unavailable |
| CTPDB_P008079_ACT_topicalpdb_0006 | Wound Healing | Skin Penetrating | Not available in the current structured import | Unknown | 0.055(+- 0.011)nmol/cm 2 h+-S.D); Iontophoresis permetaion studies; in vitro | 1630topicalpdb / linked |
| CTPDB_P008079_ACT_topicalpdb_0007 | Wound Healing | Skin Penetrating | Not available in the current structured import | Unknown | 0.122(+- 0.022)nmol/cm 2 h+-S.D; Iontophoresis permetaion studies; in vitro | 1631topicalpdb / linked |
| CTPDB_P008079_ACT_topicalpdb_0008 | Wound Healing | Skin Penetrating | Not available in the current structured import | Unknown | 0.220(+- 0.029)nmol/cm 2 h+-S.D; Iontophoresis permetaion studies; in vitro | 1632topicalpdb / linked |
| CTPDB_P008079_ACT_topicalpdb_0009 | Wound Healing | Skin Penetrating | Not available in the current structured import | Unknown | 0.509(+-0.056)nmol/cm 2 h+-S.D; Iontophoresis permetaion studies; in vitro | 1633topicalpdb / linked |
| CTPDB_P008079_ACT_topicalpdb_0010 | Wound Healing | Skin Penetrating | Not available in the current structured import | Unknown | 0.166(+- 0.050)nmol/cm 2 h+-S.D); Iontophoresis permetaion studies; in vitro | 1634topicalpdb / linked |
| CTPDB_P008079_ACT_topicalpdb_0011 | Wound Healing | Skin Penetrating | Not available in the current structured import | Unknown | 0.414(+-0.097)nmol/cm 2 h+-S.D; Iontophoresis permetaion studies; in vitro | 1635topicalpdb / linked |
| CTPDB_P008079_ACT_topicalpdb_0012 | Wound Healing | Skin Penetrating | Not available in the current structured import | Unknown | 1.30(+- 0.14)nmol/cm 2 h+-S.D; Iontophoresis permetaion studies; in vitro | 1636topicalpdb / linked |
| CTPDB_P008079_ACT_topicalpdb_0013 | Wound Healing | Skin Penetrating | Not available in the current structured import | Unknown | 2.71(+- 0.25)nmol/cm 2 h+-S.D; Iontophoresis permetaion studies; in vitro | 1637topicalpdb / linked |
| CTPDB_P008079_ACT_topicalpdb_0014 | Wound Healing | Skin Penetrating | Not available in the current structured import | Unknown | 61.6(cm/sec) * 10 8; permeability coefficient for transdermal iontophoretic transport of peptide/ protein drugs from polyacrylamide hydrogels was measured.; in vitro | 1645topicalpdb / linked |
| CTPDB_P008079_ACT_topicalpdb_0015 | Wound Healing | Skin Penetrating | Not available in the current structured import | Unknown | 10.6 (cm/sec) * 10 8; permeability coefficient for transdermal iontophoretic transport of peptide/ protein drugs from p-HEMA was measured.; in vitro | 1648topicalpdb / linked |
Sequence-linked cross-layer evidence
Linked primary-literature evidence
14
Records
1
Papers
10
Positive
4
Negative
1
Primary identities
These observations were collected directly from primary literature and linked by identical normalized sequence. They remain a separate evidence layer and do not overwrite Integrated source-database annotations.
Provenance
Source database records (22)
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
thpdb
Th1056_10375_rec0
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Raw sequence
CYFQNCPRG
Citation trail
Literature (6 records)
-
-
-
-
{"pubmed_id": "[NA](https://www.ncbi.nlm.nih.gov/pubmed/?term=NA)"}
-
--
-
-
-
-
-
-
IP evidence
Patents (2)
US 10351599
dramp
WO 2019169504
dramp
Audit surface
Raw annotations and release metadata
Integrated record last updated: 2026-04-15T00:59:13.602083+00:00
Modification summary
No structured modification annotations are available for this record.
ADMET
{
"toxicity": [
{
"source_db": "thpdb",
"assay_method": "Vasopressin overdose is expected to present with consequences related to excessive vasoconstriction of peripheral, mesenteric, coronary vascular beds, hyponatremia, and possibly with ventricular tachy",
"toxicity_type": "Toxicity"
}
]
}Source metadata
[
{
"source_db": "b3pdb",
"organism_name": "Unknown"
},
{
"source_db": "dramp",
"organism_name": "Unknown"
},
{
"source_db": "satpdb",
"organism_name": "Unknown"
},
{
"source_db": "thpdb",
"organism_name": "Unknown"
},
{
"source_db": "topicalpdb",
"organism_name": "Unknown"
}
]Structure metadata
{
"source_db": "satpdb",
"dssp_states": "CCSSCCCCC"
}