Primary literature evidence
Search paper-level observations with their value, target, assay, evidence sentence, source location, and stable record links. Evidence without a safely standardized sequence remains visible without being misrepresented as a canonical peptide.
Evidence records
In the in vitro assay, the murine rAPA (mrAPA) showed a substantial cleavage of aspartate from Ang II (22,437 ± 3358 RFU, N = 12).
Recombinant APA accelerated the return of the SBP to pre-infusion levels elicited by ... Ang II (Figure 4 in the middle panel) (p = 0.0082).
Compared to WT mice, Ang II caused an exaggerated increase in SBP in APAKO mice (Figure 5). p = 0.0196.
The hypertensive effect of Ang II was quickly abolished by the administration of rACE2 (p = 0.02) (Figure 7). Over ten minutes p = 0.0248.
The apparent permeability coefficient (Papp) of the loaded NLCs was 1.93 ± 0.11 (×10⁻⁵) cm/s
steady-state flux (Jss) of 1.65 ± 0.09 (×10⁻²) µg/cm²·s
Ang II-loaded NLCs (9.35 ± 1.36%) after 2 h
free Ang II solution remained below the quantification limit in the receptor compartment under the tested conditions
Names such as P1, PEP1, or peptide 1 are paper-local labels. Search results group them by publication and never assume cross-paper molecular identity without sequence or explicit structural evidence.
