Primary experimental recordPositive observation

PMC9788686::ACT054787

LH12

Evidence text

Paper-level observation

Only at a high concentration of 128 μg/mL would LH12 show slight cytotoxicity on HGECs with an inhibition ratio around 9.64% but without a significant reduction of the OD450 value after 45 min treatment. Figure 3a.

textConfidence: medium

Assay observation

Activity

Toxicity

Subtype

Cytotoxic

Measure

percent_inhibition

Comparator

Raw observation

9.64%

Normalized measurement

=9.64%

Value minimum

Not reported by source

Value maximum

Not reported by source

Target

HGECs

Assay method

Not reported by source

Sequence

GLLHLLHHLLHHNH

Standardization

ready simple

Source publication

Targeting cariogenic pathogens and promoting competitiveness of commensal bacteria with a novel pH-responsive antimicrobial peptide

Journal of Oral Microbiology · 2023

DOI 10.1080/20002297.2022.2159375 PMC9788686

Parent mention

Related peptide identities

PEPDIA-PLP-001008

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.