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Primary experimental recordNegative / threshold

PMC13138602::ACT044656

Phoenixin-14 amide

Evidence text

Paper-level observation

Table 1: Estradiol (ng/L) PNX 2.5 group 54.58 ± 5.85. Text: While the lowest level was observed in the PNX 2.5 nmol group (54.58 ± 5.85 ng/L), higher PNX-14 doses (PNX 5: 74.67 ± 7.62; PNX 30: 71.43 ± 5.59 ng/L) did not significantly differ from the PCOS group, indicating no robust estradiol recovery with treatment.
tableConfidence: medium

Assay observation

Activity
Metabolic/Cardiovascular
Subtype
Other
Measure
other
Comparator
=
Raw observation
54.58 ± 5.85 other
Normalized measurement
=54.58 other
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Rattus norvegicus
Assay method
Not reported by source
Sequence
DVQPPGLKVWSDPFNH
Standardization
ready simple

Source publication

Phoenixin-14 ameliorates ovarian morphology in a DHEA-induced rat model of PCOS

Reproduction & Fertility · 2026

Related peptide identities

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.