Primary experimental recordPositive observation

PMC13138602::ACT044641

Phoenixin-14 amide

Evidence text

Paper-level observation

All PNX-14-treated groups exhibited a reduction in weight gain compared to PCOS (23 ± 2.1%, 21 ± 1.8%, and 20 ± 1.6%, respectively), with statistically significant differences observed in the 5 nmol group (P < 0.05).

textConfidence: medium

Assay observation

Activity

Metabolic/Cardiovascular

Subtype

Other

Measure

other

Comparator

Raw observation

23 ± 2.1%

Normalized measurement

=23%

Value minimum

Not reported by source

Value maximum

Not reported by source

Target

Rattus norvegicus

Assay method

Not reported by source

Sequence

DVQPPGLKVWSDPFNH

Standardization

ready simple

Source publication

Phoenixin-14 ameliorates ovarian morphology in a DHEA-induced rat model of PCOS

Reproduction & Fertility · 2026

DOI 10.1530/RAF-25-0142 PMC13138602

Parent mention

Related peptide identities

PEPDIA-PLP-000501

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.