PepDiana
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Primary experimental recordPositive observation

PMC13117951::ACT043847

DVGRG

Evidence text

Paper-level observation

pretreatment with 200 μM tuna peptides S1, S5, S6, and S7 significantly increased the Bcl-2/Bax mRNA expression ratio compared to the model group, with highly significant differences (p < 0.001). (Figure 11C)
textConfidence: medium

Assay observation

Activity
Anticancer
Subtype
Not reported by source
Measure
other
Comparator
=
Raw observation
significantly increased Bcl-2/Bax mRNA ratio
Normalized measurement
=2
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Mus musculus
Assay method
Not reported by source
Sequence
DVGRG
Standardization
ready simple

Source publication

Antioxidant Peptides from Skipjack tuna: Ameliorate Function on Cigarette Smoke Extract-Induced COPD in Cell Model by Targeting Oxidative Stress, Inflammation and Apoptosis

Marine Drugs · 2026

DOI 10.3390/md24040140 PMC13117951
Parent mention

Related peptide identities

PEPDIA-PLP-000492

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.