PepDiana
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Primary experimental recordPositive observation

PMC12972984::ACT039565

MAVP

Evidence text

Paper-level observation

in vitro assays demonstrated that MAVP exerted a stronger inhibitory effect than AVP, significantly suppressing both VEGFR2 phosphorylation (p-VEGFR2) and VEGFA expression in HUVECs (Fig. S11).
textConfidence: medium

Assay observation

Activity
Other
Subtype
Antibacterial
Measure
percent_inhibition
Comparator
=
Raw observation
stronger inhibitory effect than AVP; significantly suppressed p-VEGFR2 and VEGFA expression
Normalized measurement
=1
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
HUVEC
Assay method
Not reported by source
Sequence
MAGGGATWLPPR
Standardization
ready simple

Source publication

Targeting VEGFR2 inhibition within a spatially-confined conduit promotes nerve self-resolution and alleviates mechanical allodynia

Bioactive Materials · 2026

DOI 10.1016/j.bioactmat.2026.03.009 PMC12972984
Parent mention

Related peptide identities

PEPDIA-PLP-001965

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.