PepDiana
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Primary experimental recordPositive observation

PMC12182627::ACT019131

C1

Evidence text

Paper-level observation

The IC 50 values were found to be 125.86 and 97.76 µg/mL for HSV-1 and HSV-2 infections, respectively
textConfidence: high

Assay observation

Activity
Antiviral
Subtype
Anti-HSV
Measure
IC50
Comparator
=
Raw observation
97.76 µg/mL
Normalized measurement
=97.76 µg/mL
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Vero
Assay method
Viral entry inhibition assay
Sequence
LQYPDDSDDE
Standardization
ready simple
Assay conditions
"10 TCID50 virus pre-attached at 4 °C for 2 h, then peptide added for 1 h at 37 °C. MTT readout after 5 days."

Source publication

Uncovering the Anti-Herpetic Activity of Anionic Peptides Derived From the Cytoplasmic Domain of Nectin-1.

Bioinformatics and Biology Insights · 2025

DOI 10.1177/11779322251344130 PMC12182627
Parent mention

Related peptide identities

PEPDIA-PLP-001878

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.