PepDiana
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Primary experimental recordPositive observation

PMC12182627::ACT019129

C1

Evidence text

Paper-level observation

Peptide C1 offered 62.03% protection against HSV-1 and 59.38% protection against HSV-2 infections at 250 µg/mL in the viral attachment inhibition assay.
textConfidence: high

Assay observation

Activity
Antiviral
Subtype
Anti-HSV
Measure
percent_inhibition
Comparator
=
Raw observation
59.38%
Normalized measurement
=59.38%
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Vero
Assay method
Viral attachment inhibition assay
Sequence
LQYPDDSDDE
Standardization
ready simple
Assay conditions
"250 µg/mL peptide, peptide and 10 TCID50 virus added to Vero cells, incubated at 4 °C for 2 h. MTT readout after 5 days."

Source publication

Uncovering the Anti-Herpetic Activity of Anionic Peptides Derived From the Cytoplasmic Domain of Nectin-1.

Bioinformatics and Biology Insights · 2025

DOI 10.1177/11779322251344130 PMC12182627
Parent mention

Related peptide identities

PEPDIA-PLP-001878

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.