PepDiana
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Primary experimental recordPositive observation

PMC12182627::ACT019123

C1

Evidence text

Paper-level observation

In the viral inactivation assay, peptide C1 at 250 µg/mL reduced ... HSV-2 infections by ... 67.16%, respectively, with IC 50 values of ... 111.13 µg/mL
textConfidence: high

Assay observation

Activity
Antiviral
Subtype
Anti-HSV
Measure
IC50
Comparator
=
Raw observation
111.13 µg/mL
Normalized measurement
=111.13 µg/mL
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Vero
Assay method
Viral inactivation assay
Sequence
LQYPDDSDDE
Standardization
ready simple
Assay conditions
"10 TCID50 virus pre-incubated with peptide for 1 h at 37 °C, then added to Vero cells for 2 h. MTT readout after 5 days."

Source publication

Uncovering the Anti-Herpetic Activity of Anionic Peptides Derived From the Cytoplasmic Domain of Nectin-1.

Bioinformatics and Biology Insights · 2025

DOI 10.1177/11779322251344130 PMC12182627
Parent mention

Related peptide identities

PEPDIA-PLP-001878

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.