PepDiana
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Primary experimental recordPositive observation

PMC10126514::ACT000313

P21

Evidence text

Paper-level observation

Figure 4: P21 makes the fluorescence intensity of Aβ1-42 aggregation significantly lower than that of the Aβ group (p < 0.05), which can achieve 100% inhibition.
textConfidence: medium

Assay observation

Activity
Other
Subtype
Anti-Aggregation
Measure
percent_inhibition
Comparator
=
Raw observation
100% inhibition (p<0.05)
Normalized measurement
=100%
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Aβ1-42
Assay method
Not reported by source
Sequence
YVRHLKYVRHLK
Standardization
ready simple

Source publication

The interaction of peptide inhibitors and Aβ protein: Binding mode analysis, inhibition of the formation of Aβ aggregates, and then exert neuroprotective effects.

Frontiers in Aging Neuroscience · 2023

DOI 10.3389/fnagi.2023.1139418 PMC10126514
Parent mention

Related peptide identities

PEPDIA-PLP-003361

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.