PepDiana
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Primary experimental recordNegative / threshold

PMC10043419::ACT000061

MPI-C

Evidence text

Paper-level observation

However, a non-carcinomatous cell named bEnd.3 ... exhibited no viability suppression when being treated with different OMVs at the concentration of <100 μg/ml (Figure S5), indicating the specific destruction ability of MPI fusion peptides in bioengineered OMVs to tumor cells.
supplementConfidence: medium

Assay observation

Activity
Anticancer
Subtype
Cytotoxic
Measure
cell_viability
Comparator
<
Raw observation
no viability suppression at <100 μg/ml
Normalized measurement
<100 µg/mL
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
bEnd.3
Assay method
Not reported by source
Sequence
Not reported by source
Standardization
insufficient information

Source publication

Bioengineered bacterial outer membrane vesicles encapsulated Polybia–mastoparan I fusion peptide as a promising nanoplatform for bladder cancer immune-modulatory chemotherapy

Frontiers in Immunology · 2023

DOI 10.3389/fimmu.2023.1129771 PMC10043419
Parent mention

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.