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Paper-scoped peptide mentionSequence reported

NY-ESO-1

PMC12891685::PEP000003

Source publication

Immune checkpoint inhibition increases antigen-specific T cell response in head and neck cancer

Scientific Reports · 2026

Sequence status
reported
Standardization
Sequence ready
Source location
unknown
Activity records
6

Sequence evidence

Reported molecular identity

SLLMWITQC

SLLMWITQC

Resolved peptide links

Experimental observations

Records linked to this mention

ImmunomodulatoryAntibacterialPositive observation
Record detail

The increase of NY-ESO-1 to NY-ESO-1/anti-PD-1 in R was significant, with an increase of >60% in IFNγ (Fig. 3E,F).

Measure
fold_change
Value
increase of >60% in IFNγ
Target
Homo sapiens
Assay
Not reported by source
Source publication
ImmunomodulatoryAntibacterialPositive observation
Record detail

The increase of NY-ESO-1 to NY-ESO-1/anti-PD-1 in R was significant, with an increase of ... >100% in GrB (Fig. 3G,H).

Measure
fold_change
Value
increase of >100% in GrB
Target
Homo sapiens
Assay
Not reported by source
Source publication
ImmunomodulatoryAntibacterialNegative / threshold
Record detail

The IFNγ/GrB-ELISPOT results show in principle that LAG-3 has no effect either alone or in combination with anti-PD-1 (Fig. 4A).

Measure
fold_change
Value
no effect
Target
Homo sapiens
Assay
Not reported by source
Source publication
ImmunomodulatoryAntibacterialNegative / threshold
Record detail

The IFNγ/GrB-ELISPOT results show in principle that LAG-3 has no effect either alone or in combination with anti-PD-1 (Fig. 4B).

Measure
fold_change
Value
no effect
Target
Homo sapiens
Assay
Not reported by source
Source publication
ImmunomodulatoryAntibacterialNegative / threshold
Record detail

The same applies to TIM-3, which does not elicit an immune response either alone or in combination with anti-PD-1 (Fig. 4C).

Measure
fold_change
Value
no effect
Target
Homo sapiens
Assay
Not reported by source
Source publication
ImmunomodulatoryAntibacterialNegative / threshold
Record detail

The same applies to TIM-3, which does not elicit an immune response either alone or in combination with anti-PD-1 (Fig. 4D).

Measure
fold_change
Value
no effect
Target
Homo sapiens
Assay
Not reported by source
Source publication

Local peptide labels such as P1, PEP1, or peptide 1 are grouped only within this paper and are not assumed to represent the same molecule across publications.