AntimicrobialAntibacterialPositive observation
Record detail the MICs of anoplin (Fig. 3a and Tables S1 and S2) ranged from 0.8 to 6.3 μmol L−1.
- Measure
- MIC
- Value
- 0.8–6.3 μmol L−1
- Target
- multiple bacteria
- Assay
- Not reported by source
Source publication
Molecular hybridization strategy for tuning bioactive peptide function.
Communications Biology · 2023
- Sequence status
- reported
- Standardization
- Sequence ready
- Source location
- unknown
- Activity records
- 4
Sequence evidence
Reported molecular identity
GLLKRIKTLL
GLLKRIKTLL
Resolved peptide links
Experimental observations
Records linked to this mention
AntimicrobialAntiparasiticPositive observation
Record detail anoplin yielded 90% fluorescent sporozoites ... at 0.8 μmol L−1 (Fig. 3d and Table S1).
- Measure
- percent_inhibition
- Value
- 90% fluorescent sporozoites
- Target
- Plasmodium gallinaceum
- Assay
- Not reported by source
ToxicityHemolyticPositive observation
Record detail Anoplin was hemolytic at 50 μmol L−1 (Fig. 3f, Table S1, and Supplementary Data 1).
- Measure
- hemolysis
- Value
- hemolytic at 50 μmol L−1
- Target
- Homo sapiens
- Assay
- Not reported by source
ToxicityCytotoxicNegative / threshold
Record detail After 24 h of incubation, we did not observe peptide-meditated cytotoxicity towards MCF-10A cells (Fig. 3e).
- Measure
- cell_viability
- Value
- did not observe peptide-meditated cytotoxicity
- Target
- MCF-10A
- Assay
- Not reported by source
Local peptide labels such as P1, PEP1, or peptide 1 are grouped only within this paper and are not assumed to represent the same molecule across publications.