Paper-scoped peptide mentionSequence not reported or unresolved

[K2,5]-Lol

PMC10178204::PEP000003

Source publication

Peptaibol Analogs Show Potent Antibacterial Activity against Multidrug Resistant Opportunistic Pathogens

International Journal of Molecular Sciences · 2023

DOI 10.3390/ijms24097997 PMC10178204 PMID 37175704

Sequence status: not reported or unresolved
Standardization: ready modified
Source location: unknown
Activity records: 25

Sequence evidence

Reported molecular identity

The publication reports a peptide label or compound identity, but no sequence could be safely standardized from the available text, table, figure, or structure context.

Oct-Aib-Lys-Leu-Aib-Lys-Gly-Leu-Aib-Gly-Ile-Lol

Experimental observations

Records linked to this mention

AntimicrobialAntibacterialPositive observation

Record detail

Table 2: 1 [K2,5]-Lol, Bsu MIC 4 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 4 µg/mL
Target: Bacillus subtilis
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 2: 1 [K2,5]-Lol, Efa MIC 2 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 2 µg/mL
Target: Enterococcus faecalis
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 2: 1 [K2,5]-Lol, Spy MIC 2 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 2 µg/mL
Target: Streptococcus pyogenes
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 2: 1 [K2,5]-Lol, Sau MIC 16 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 16 µg/mL
Target: Staphylococcus aureus
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 2: 1 [K2,5]-Lol, Eco MIC 32 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 32 µg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Record detail

Table 2: 1 [K2,5]-Lol, Kpn MIC >128 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: >128 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 2: 1 [K2,5]-Lol, Aba MIC 4 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 4 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 2: 1 [K2,5]-Lol, Pae MIC 16 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 16 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

ToxicityHemolyticNegative / threshold

Record detail

Table 2: 1 [K2,5]-Lol, Hemolysis -* (limited hemolysis, zone not defined)

Mention PMC10178204::PEP000003PMC10178204table

Measure: hemolysis
Value: -*
Target: Not reported by source
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, S. aureus ATCC 43300 (MRSA) MIC 2 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 2 µg/mL
Target: Staphylococcus aureus
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, S. aureus ATCC 43300 (MRSA) MBC 2 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MBC
Value: 2 µg/mL
Target: Staphylococcus aureus
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, A. baumannii SI-12 (OXA-23) MIC 4 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 4 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, A. baumannii SI-12 (OXA-23) MBC 8 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MBC
Value: 8 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, A. baumannii SI-648 (OXA-23, OXA-51-like) MIC 8 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 8 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, A. baumannii SI-648 (OXA-23, OXA-51-like) MBC 16 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MBC
Value: 16 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, A. baumannii SI-310 (OXA-24) MIC 4 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 4 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, A. baumannii SI-310 (OXA-24) MBC 4 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MBC
Value: 4 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, P. aeruginosa VR-143/97 (VIM-1) MIC 32 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 32 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, P. aeruginosa VR-143/97 (VIM-1) MBC 32 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MBC
Value: 32 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, P. aeruginosa VA-182/00 (VIM-2) MIC 16 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 16 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, P. aeruginosa VA-182/00 (VIM-2) MBC 16 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MBC
Value: 16 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, P. aeruginosa 506/99 (VIM-2) MIC 16 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 16 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, P. aeruginosa 506/99 (VIM-2) MBC 32 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MBC
Value: 32 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, P. aeruginosa 101/1477 (IMP-1) MIC 8 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MIC
Value: 8 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Record detail

Table 3: 1, P. aeruginosa 101/1477 (IMP-1) MBC 16 µg/mL

Mention PMC10178204::PEP000003PMC10178204table

Measure: MBC
Value: 16 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

Local peptide labels such as P1, PEP1, or peptide 1 are grouped only within this paper and are not assumed to represent the same molecule across publications.