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Paper-scoped peptide mentionSequence not reported or unresolved

BB

PMC10137466::PEP000001

Source publication

Novel Property Cytotoxicity and Mechanism of Food Preservative Brevilaterins against Human Gastric Cancer Cells

Foods · 2023

Sequence status
not reported or unresolved
Standardization
Sequence unresolved
Source location
unknown
Activity records
12

Sequence evidence

Reported molecular identity

The publication reports a peptide label or compound identity, but no sequence could be safely standardized from the available text, table, figure, or structure context.

Experimental observations

Records linked to this mention

AnticancerCytotoxicPositive observation
Record detail

Specifically, as the concentration increased from 2.0 µg/mL to 16.0 µg/mL, the viability of gastric cancer cells BGC-823 significantly decreased... 8.0 µg/mL of BB/BC strongly inhibited the viability of cancer cells BGC-823

Measure
cell_viability
Value
significantly decreased viability at 2.0-16.0 µg/mL
Target
Homo sapiens
Assay
Not reported by source
Source publication
AnticancerCytotoxicPositive observation
Record detail

8.0 µg/mL of BB/BC strongly inhibited the viability of cancer cells BGC-823 while having minimal effect on its corresponding human normal gastric epithelial cells, GES-1

Measure
cell_viability
Value
minimal effect on GES-1 at 8.0 µg/mL
Target
Homo sapiens
Assay
Not reported by source
Source publication
AnticancerCytotoxicPositive observation
Record detail

treatment with 4.0 µg/mL and 6.0 µg/mL of BB for 48 h resulted in significantly decreased scratch-healing rates of BGC-823, at 58.91% and 51.53%, respectively, in contrast to the control group's rate of 94.57%

Measure
percent_inhibition
Value
58.91%
Target
Homo sapiens
Assay
Not reported by source
Source publication
AnticancerCytotoxicPositive observation
Record detail

treatment with 4.0 µg/mL and 6.0 µg/mL of BB for 48 h resulted in significantly decreased scratch-healing rates of BGC-823, at 58.91% and 51.53%, respectively, in contrast to the control group's rate of 94.57%

Measure
percent_inhibition
Value
51.53%
Target
Homo sapiens
Assay
Not reported by source
Source publication
AnticancerCytotoxicPositive observation
Record detail

The LDH release rate in BGC-823 cells increased from 113.41% to 153.78% as the concentration of BB increased from 4 µg/mL to 8 µg/mL.

Measure
other
Value
113.41%
Target
Homo sapiens
Assay
Not reported by source
Source publication
AnticancerCytotoxicPositive observation
Record detail

The LDH release rate in BGC-823 cells increased from 113.41% to 153.78% as the concentration of BB increased from 4 µg/mL to 8 µg/mL.

Measure
other
Value
153.78%
Target
Homo sapiens
Assay
Not reported by source
Source publication
AnticancerCytotoxicPositive observation
Record detail

At concentrations of 4 µg/mL, 6 µg/mL, and 8 µg/mL of BB, approximately 18.68%, 22.25%, and 36.69% of cancer cells underwent apoptosis, respectively

Measure
percent_inhibition
Value
18.68%
Target
Homo sapiens
Assay
Not reported by source
Source publication
AnticancerCytotoxicPositive observation
Record detail

At concentrations of 4 µg/mL, 6 µg/mL, and 8 µg/mL of BB, approximately 18.68%, 22.25%, and 36.69% of cancer cells underwent apoptosis, respectively

Measure
percent_inhibition
Value
22.25%
Target
Homo sapiens
Assay
Not reported by source
Source publication
AnticancerCytotoxicPositive observation
Record detail

At concentrations of 4 µg/mL, 6 µg/mL, and 8 µg/mL of BB, approximately 18.68%, 22.25%, and 36.69% of cancer cells underwent apoptosis, respectively

Measure
percent_inhibition
Value
36.69%
Target
Homo sapiens
Assay
Not reported by source
Source publication
AnticancerCytotoxicPositive observation
Record detail

the DCFH positive ratio of BGC-823 cells showed an increase, peaking at 14.28%, 54.35%, and 72.77% after 24 h of exposure to 4, 6, and 8 µg/mL of BB, respectively.

Measure
other
Value
14.28%
Target
Homo sapiens
Assay
Not reported by source
Source publication
AnticancerCytotoxicPositive observation
Record detail

the DCFH positive ratio of BGC-823 cells showed an increase, peaking at 14.28%, 54.35%, and 72.77% after 24 h of exposure to 4, 6, and 8 µg/mL of BB, respectively.

Measure
other
Value
54.35%
Target
Homo sapiens
Assay
Not reported by source
Source publication
AnticancerCytotoxicPositive observation
Record detail

the DCFH positive ratio of BGC-823 cells showed an increase, peaking at 14.28%, 54.35%, and 72.77% after 24 h of exposure to 4, 6, and 8 µg/mL of BB, respectively.

Measure
other
Value
72.77%
Target
Homo sapiens
Assay
Not reported by source
Source publication

Local peptide labels such as P1, PEP1, or peptide 1 are grouped only within this paper and are not assumed to represent the same molecule across publications.