MetaADEDB 2.0 @ LMMD
Urofollitropin
(ZDRRIRUAESZNIH-BZGUUIOASA-N)
Structure
SMILES
CC[C@@H]([C@@H]1NC(=O)[C@H](Cc2ccc(cc2)O)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)[C@H](O)C)CC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N)CC(C)C)C
Molecular Formula:
C42H65N11O12S2
Molecular Weight:
980.162
Log P:
0.9713
Hydrogen Bond Acceptor:
25
Hydrogen Bond Donor:
12
TPSA:
427.27
CAS Number(s):
97048-13-0
Synonym(s)
1.
Urofollitropin
2.
Follicle-Stimulating Hormone, Human Urine
3.
Bravelle
4.
Fertinex
5.
Follitrin
6.
Human FSH, Urinary
7.
Metrodin
8.
Metrodin HP
9.
Metrodin High Purity
10.
Neo Fertinorm
11.
Follicle Stimulating Hormone, Human Urine
12.
High Purity, Metrodin
13.
Urinary Human FSH
External Link(s)
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 26
Canada Vigilance: 71
Canada Vigilance
US FAERS
2NauseaFAERS: 4SIDER
US FAERS
3Biochemical pregnancyFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
4Chest PainFAERS: 1SIDER
US FAERS
5DehydrationFAERS: 1SIDER
US FAERS
6DizzinessFAERS: 1SIDER
US FAERS
7FatigueFAERS: 1SIDER
US FAERS
8HaemoconcentrationFAERS: 1US FAERS
9HeadacheFAERS: 1
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
10LeukopeniaFAERS: 1SIDER
US FAERS
11Low birth weight babyFAERS: 1US FAERS
12No reaction on previous exposure to drugFAERS: 1US FAERS
13Ovarian Hyperstimulation SyndromeFAERS: 1SIDER
US FAERS
14PainFAERS: 1SIDER
US FAERS
15StillbirthFAERS: 1US FAERS
16ThrombocytopeniaFAERS: 1US FAERS
17UrticariaFAERS: 1SIDER
US FAERS
18Visual ImpairmentFAERS: 1US FAERS
19VomitingFAERS: 1SIDER
US FAERS
20Abdominal CrampsSIDER
21Abdominal PainSIDER
22Abdominal bloatingSIDER
23Abdominal discomfortSIDER
24AbscessSIDER
25AcheSIDER
26AcneSIDER
27Adnexa uteri painSIDER
28AlopeciaSIDER
29Anaphylactic shockSIDER
30Anaphylactoid ReactionSIDER
31AnorexiaSIDER
32AnxietySIDER
33ArthralgiaSIDER
34ArthropathySIDER
35Aspartate Aminotransferase IncreasedSIDER
36AstheniaSIDER
37AsthmaSIDER
38AtelectasisSIDER
39BREAST PAIN FEMALESIDER
40Back PainSIDER
41Bladder painSIDER
42Blood and lymphatic system disordersSIDER
43Blood lactate dehydrogenase increasedSIDER
44Blood urea increasedSIDER
45Breast tendernessSIDER
46BronchitisSIDER
47Cervical dysplasiaCanada Vigilance: 1Canada Vigilance
48ChillsSIDER
49ConjunctivitisSIDER
50ConstipationSIDER
51Cramps of lower extremitiesSIDER
52CystitisSIDER
53CystSIDER
54DependenceSIDER
55DermatitisSIDER
56Dermoid CystSIDER
57DiscomfortSIDER
58DistressSIDER
59Drug abuseSIDER
60Dry skinSIDER
61DyspepsiaSIDER
62DysuriaSIDER
63Ectopic PregnancySIDER
64EczemaSIDER
65EmbolismSIDER
66Emotional distressSIDER
67Enlargement abdomenSIDER
68ErythemaSIDER
69Exacerbation of asthmaSIDER
70Feeling abnormalSIDER
71FertilizationSIDER
72FlatulenceSIDER
73Fullness abdominalSIDER
74Gastrointestinal PainSIDER
75General symptomSIDER
76Genital HerpesSIDER
77Genital infectionSIDER
78Genital painSIDER
79Hip DislocationSIDER
80Hormone level abnormalCanada Vigilance: 1Canada Vigilance
81Hydatidiform MoleSIDER
82HydrocephalusSIDER
83HyperemesisSIDER
84HypersensitivitySIDER
85HypotensionSIDER
86IndurationSIDER
87InfectionSIDER
88InfestationSIDER
89Influenza-like symptomsSIDER
90InfluenzaSIDER
91Injection Site ReactionSIDER
92Injection site bruisingSIDER
93Injection site inflammationSIDER
94Injection site irritationSIDER
95Injection site painSIDER
96LeukorrheaSIDER
97Local reactionSIDER
98Low Back PainSIDER
99LymphadenopathySIDER
100MalaiseSIDER
101MeningoceleSIDER
102MenorrhagiaSIDER
103MetrorrhagiaSIDER
104Mood swingsSIDER
105Multiple PregnancySIDER
106Musculoskeletal discomfortSIDER
107MyalgiaSIDER
108NasopharyngitisSIDER
109Neck PainSIDER
110NephrolithiasisSIDER
111NervousnessSIDER
112NeutropeniaSIDER
113Nipple painSIDER
114Oropharyngeal discomfortSIDER
115Oropharyngeal painSIDER
116Otitis MediaSIDER
117Ovarian enlargementSIDER
118Ovarian hyperstimulationSIDER
119Ovarian painSIDER
120PalpitationsSIDER
121Pelvic PainSIDER
122Pelvic discomfortSIDER
123Pelvic pain femaleSIDER
124PharyngitisSIDER
125Pharyngolaryngeal PainSIDER
126Pilonidal CystSIDER
127PneumothoraxSIDER
128PregnancySIDER
129PresyncopeSIDER
130PruritusSIDER
131Puerperal pyrexiaSIDER
132Reaction febrileSIDER
133Red blood cells semen positiveSIDER
134RednessSIDER
135RhinitisSIDER
136SepsisSIDER
137ShockSIDER
138SinusitisSIDER
139SomnolenceSIDER
140SpermatoceleSIDER
141Spotting vaginalSIDER
142SweatingSIDER
143SwellingSIDER
144SyncopeSIDER
145TachycardiaSIDER
146TensionSIDER
147Therapy non-responderCanada Vigilance: 1Canada Vigilance
148ThirstSIDER
149Throat irritationSIDER
150ThromboembolismSIDER
151ThrombosisSIDER
152ToothacheSIDER
153Torsion of ovarySIDER
154Ulcerative stomatitisSIDER
155Upset stomachSIDER
156Urinary IncontinenceSIDER
157Urinary tract infectionSIDER
158Uterine spasmSIDER
159Vaginal DischargeSIDER
160VaricoceleSIDER
161Vulvovaginal pruritusSIDER
162VulvovaginitisSIDER
163nervous system disorderSIDER
164ovarian neoplasmSIDER
165treatment failureCanada Vigilance: 1Canada Vigilance
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